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A member asked:
Help please! is cancer caused by an extra chromosome or a lack of a chromosomes?
A doctor has provided 1 answer
Neither: cancer is caused by mutation in well defined genes that first lead to immortality and then the production of proteins that stimulate the cell to behave in an aggressive fashion. In Rous Sarcoma, the virus enters the Src gene causing a mutation giving rise to production of Src protein. Inhibition of Src gene causes sarcoma to revert to normal fibroblast.
Answered 6/12/2017
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