U.S. doctors online nowAsk doctors free
A 36-year-old male asked:

Hello, is it true that the effect of paxil (paroxetine) and wellbutrin both become less or insignificant by the time (work to limit time then not working in body).

1 doctor answer5 doctors weighed in
Dr. Donald Jacobson
A Verified Doctoranswered
41 years experience
It can happen with: Any antidepressant. We do not know why this happens. We also unfortunately do not have any comparative data on the antidepressants in this regard. Clinically i would say that I have seen Prozac last the longest without requiring change (unpublished data from my practice). We have two year data on Paxil (paroxetine) in this regard. When it happens, we augment or switch. Godt nytt år!
Last updated Jan 27, 2015


Content on HealthTap (including answers) should not be used for medical advice, diagnosis, or treatment, and interactions on HealthTap do not create a doctor-patient relationship. Never disregard or delay professional medical advice in person because of anything on HealthTap. Call your doctor or 911 if you think you may have a medical emergency.