A member asked:

What are the different causes down syndrome?

4 doctors weighed in across 2 answers

Downs syndrome: Trisomy 21 when there is an extra chromosome at 21, mosaicism when some cells have trisomy and others not, robertson translocation [n which long arm of 21 chromosome is attached to another chromosome often chromosome 14.

Answered 9/8/2014

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W varieties: The most common cause is trisomy 21, a situation with 3 number 21 chromosomes. A second possibility is a partial translocation of a piece of a 21 chromosome onto another chromosome.

Answered 6/19/2015

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