A 32-year-old member asked:
Which type of mutation causes down syndrome?
2 doctor answers • 3 doctors weighed in
Dr. James Fergusonanswered
Pediatrics 48 years experience
No : Down syndrome is an abnormality of chromosome numbers, not a trait or mutation in the gene code. During conception only one of chromosome of each pair is given by both parents to the fertile egg.If a parent adds their 2 nbr 21chm to the other parents nbr 21, 3 end up in the egg ; the excess 21 causes the all the problems.Rare forms are causes by a extra piece of a 21, but that's another issue.
Created for people with ongoing healthcare needs but benefits everyone.
4.9k viewsAnswered >2 years ago
Dr. Osman Farooqanswered
Pediatrics - Neurology 22 years experience
Trisomy 21: Down syndrome is also called trisomy 21. That means that there is a partial or complete third copy of the chromosome 21. It is the most common chromosomal abnormality.
Created for people with ongoing healthcare needs but benefits everyone.
4.9k viewsReviewed >2 years ago
Similar questions
A 49-year-old member asked:
Which type of chromosomal mutation causes down syndrome?
2 doctor answers • 3 doctors weighed in
Dr. Osman Farooqanswered
Pediatrics - Neurology 22 years experience
Trisomy 21: Down syndrome is also called trisomy 21. That means that there is a partial or complete third copy of the chromosome 21. It is the most common chromosomal abnormality.
Created for people with ongoing healthcare needs but benefits everyone.
4.9k viewsAnswered >2 years ago
Last updated Feb 11, 2020
People also asked
Connect with a U.S. board-certified doctor by text or video anytime, anywhere.
$44 video appointments with $19/month membership*
*Billed $57 every 3 months. Cancel anytime.
Disclaimer:
Content on HealthTap (including answers) should not be used for medical advice, diagnosis, or treatment, and interactions on HealthTap do not create a doctor-patient relationship. Never disregard or delay professional medical advice in person because of anything on HealthTap. Call your doctor or 911 if you think you may have a medical emergency.
