A member asked:

What is sickle cell anemia's effect on fertility and reproduction?

7 doctors weighed in across 2 answers
Dr. Liawaty Ho answered

Specializes in Hematology and Oncology

Significant: In men, it can cause priapism (a sustained penile erection in the absence of sexual activity/ desire)- is often underdiagnosed that leads to impotence. In women, pregnancy is associated with both fetal& maternal complication- related to compromised placental blood flow& include spontaneous abortion, growth restriction, fetal demise. Increase risk fo acute chest synd, preeclampsia, clots in mother.

Answered 4/15/2021

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Many: Low oxygen (as seen in sca) can decrease sperm counts and damage to sperm dna. For similar reasons these pregnancies can be complicated of the mom is +. Also, the genetic risk is a big deal for the baby.

Answered 4/15/2021

5.8k views

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