Discussing switching from cymbalta (duloxetine) to zoloft for ocd---afraid of weight gain on zoloft---what is likelihood of zoloft weight gain...active..watch diet?

Zoloft (sertraline) weight gain: Weight gain on zoloft (sertraline) is actually quite rare. When it does occur it tends to occur late into use, say six months to a year into use but only in approximately one or 2% of people. It is generally considered weight neutral. Of course watching weight, exercising, and watching your diet are all extremely important. Best wishes for a happy holiday season.

Agree- quite weight: neutral. According to a study published in the Journal of Clinical Psychiatry the average weight gain was 0.1% after > 1 year on zoloft (sertraline). 4.5% people treated with zoloft (sertraline) had a significant weight gain in one study. Weight gain is more likely if the person is taking zoloft (sertraline) for 6 months or longer. There are some people who experience increased carbohydrate craving on zoloft (sertraline). However, mechanism for wei

It would be best if your medication is managed by a Psychiatrist. If you are not confident with your doctor please see another for a second opinion.