Can antibiotics help with gallbladder disease?

Rarely: Studies of people with gallbladder disease show that the bile is infected only 15% of the time; the inflammation, when present, is usually do to a chemical-type irritation by the contents in the bile. Since we don't know who's bile is infected, we treat all people with acute gallbladder problems with IV antibiotics when hospitalized.

No: Antibiotics do not help with gallbladder disease except in the case of gallbladder infection, in which case they are only useful as an adjunct to surgery.

Temporarily: Most times gallbladder problems arise from gallstones which obstruct the outlet of the gallbladder causing pain and inflammation. This inflammation can become infected. When it does antibiotics will help but ultimately it will not get better untill the gallbladder is surgically removed.