A 27-year-old female asked:
Why does infection of the stomach with h.Pylori predispose to duodenal ulcers?
1 doctor answer
Dr. Emilio Perez answered
21 years experience in Geriatrics
Acid production : The precise mechanism by which h. Pylori contributes to duodenal ulcer (du) formation is not totally understood, but the bacteria appears to increased gastric acid secretion causing increased acid in duodenun, the bacteria also elicit a body immune inflammatory response and decrease the mucosal defense mechanisms on the duodenun making the mucosa more vulnerable to acid.
Answered on May 18, 2014
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