Antihistamines: Both non-sedating (Zyrtec, Allegra, (fexofenadine) Claritin) and sedating (Benadryl) over the counter antihistamines are useful for hives. Usually recommend daily treatment with non-sedating antihistamines for more chronic, persistent hives. For acute hives sedating antihistamines are fine.
Answered 12/26/2017
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