I tried desloratadine and rupatin for hives both of them helped but made agility and restlessness. can the hives go on its own without medication?

Maybe: Hives are an allergic reaction. What have you eaten differently? Using any new soaps or detergents in your wash? Try to figure out what is causing the hives. If its avoidable then the hives won't start due to avoiding the allergy trigger. Be careful more encounters increase chance of full blown reaction. See a Doctor for help with diagnosis.