Is oxycodone or other narcotics any good for pain from diabetic neuropathy?

As a last resort: While narcotics are very effective against a wide variety of pain syndromes, their side effects, tendency to cause tolerance, and addiction potential make them agents to use only if more targeted treatment (such as treatment for neuropathic pain) has failed. Often, narcotic medications must be written for and monitored by a dedicated pain clinic.

Not first choice: There continues to be debate regarding the value of opioids in the management of neuropathy. They are certainly not a first line treatment. A targeted treatment like neurontin, Lyrica (pregabalin) or Cymbalta would be better first choices.

Yes but...: Narcotics may mask the symptoms but won’t resolve the issue. Diabetic neuropathy is nerve damage and therefore can never be 100% restored. To improve and prevent further deterioration diet and exercise is the key. Keep blood sugars under control. Stop smoking (affects circulation to nerves) limit alcohol use which destroys nerves. Vit. B may levels should be checked and supplemented as required.

Not really: Narcotic medicines are curiously unhelpful for the pain of neuropathy. One problem with them is that most have a time length of action. Another problem is that a person builds tolerance to them. There are many non narcotic treatment options. It is rare that providers who treat this would consider narcotics for it.