A member asked:

Is pulmonary hypertension hereditable?

7 doctors weighed in across 4 answers
Dr. Arnon Rubin answered

Specializes in Internal Medicine

Yes: If you have primary pulmonary hypertension there are several classes of drugs to treat it. Tracleer, (bosentan) revatio, letaris are some of the drugs that can be used in the right situation.

Answered 7/7/2020

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Dr. Lokesh Guglani answered

Specializes in Pediatric Pulmonology

Yes and No: Not all forms of pulmonary hypertension are heritable. Pulmonary hypertension can develop due to severe chronic lung or heart disease, chronic thrombotic disorders, sickle cell disease & rare blood vessel disorders. Certain rare types of pulmonary hypertension associated with bmpr-2 mutations are heritable. Please consult a lung specialist for full diagnostic work up.

Answered 7/7/2020

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Dr. Charles Burger answered

Specializes in Internal Medicine - Pulmonary Critical Care

It may be inherited: Up to 5% of patients with pulmonary arterial hypertension (pah) may have a genetic or heritable cause. Research studies have identified a genetic abnormality affecting bone morphogenetic protein receptor 2 (bmpr2) that appears to predispose a patient to pah. Fortunately, even if an individual inherits the abnormal gene, the likelihood of developing pah is only 1 in 5.

Answered 4/24/2015

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Dr. Ed Friedlander answered

Specializes in Pathology

Usually not: Primary pulmonary hypertension usually strikes at random, without any clear familial tendency. Nobody understands why. Other pulmonary hypertension is secondary to some other lung disease. Best wishes.

Answered 7/7/2020

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