is pulmonary hypertension hereditary?

Question

Answer 1

Sometimes: Pulmonary hypertension is not one disease, but several, and how inherited it is depends on the type of disease and the cause. There is a type called familial pulmonary hypertension which is, by definition, inherited. Other types of pulmonary hypertension are caused by other conditions such as heart disease or sleep apneas. Blood clots to the lungs can be inherited and can also cause pulm htn.

Answer 2

Can be-usually not.: Most patients with pulmonary arterial hypertension (pah) are the only member of the family affected. Less that 10% will have an affected relative. However, genes have been identified that are associated with pah. Genetic testing can be done at some centers.

Answer 3

Sometimes: The new dana point classification of pulmonary HTN includes an hereditary class. For those pts specific genetic testing for chromosomal abnormalities is indicated.

Answer 4

It may be inherited: Up to 5% of patients with pulmonary arterial hypertension (pah) may have a genetic or heritable cause. Research studies have identified a genetic abnormality affecting bone morphogenetic protein receptor 2 (bmpr2) that appears to predispose a patient to pah. Fortunately, even if an individual inherits the abnormal gene, the likelihood of developing pah is only 1 in 5.

Answer 5

Yes: If you have primary pulmonary hypertension there are several classes of drugs to treat it. Tracleer, (bosentan) revatio, letaris are some of the drugs that can be used in the right situation.

Answer 6

Yes and No: Not all forms of pulmonary hypertension are heritable. Pulmonary hypertension can develop due to severe chronic lung or heart disease, chronic thrombotic disorders, sickle cell disease & rare blood vessel disorders. Certain rare types of pulmonary hypertension associated with bmpr-2 mutations are heritable. Please consult a lung specialist for full diagnostic work up.

Answer 7

It may be inherited: Up to 5% of patients with pulmonary arterial hypertension (pah) may have a genetic or heritable cause. Research studies have identified a genetic abnormality affecting bone morphogenetic protein receptor 2 (bmpr2) that appears to predispose a patient to pah. Fortunately, even if an individual inherits the abnormal gene, the likelihood of developing pah is only 1 in 5.

Answer 8

Usually not: Primary pulmonary hypertension usually strikes at random, without any clear familial tendency. Nobody understands why. Other pulmonary hypertension is secondary to some other lung disease. Best wishes.

Answer 9

Maybe: The disease is still rare and most patients are going undiagnosed. Because of this good data is difficult to get when those diagnosed are the minority and other factors influence who gets diagnosed. That said, there is a recent study showing mortality is worse among black women - at least in the US but this says nothing of prevalence.

Answer 10

Complicated: I'm assuming you're referring to idiopathic or primary pulmonary hypertension? I don't think there has ever been a world wide study - most studies include a registry in their own country, so i don't think the answer to your question is known. There are genetic factors so the incidence may well be different in different races.

Answer 11

Unclear: We have not noticed any difference in race in our trials, but they were not powered to find race differences.

Answer 12

Hard to tell: It depends on what the cause of it is. Obstructive sleep apnea if causing it, may be cured by weight loss and some surgical techniques, whereas primary pulmonary hypertension will not get cured but may be adequately controlled by some medications.

Answer 13

Depends: Depends on the cause. Most ph is due to lung disease. If the lung disease can be treated successfully, the ph resolves. Primary pulmonary hypertension is more difficult because there is no known cause but there are new medicines that are being used for pph with some success.

Answer 14

PH Cure: There are 9 available medications for pulmonary arterial hypertension (pah). The treatment can be quite effective but does not generally cure pah. Lung transplant can cure the disease but has other significant issues.

Answer 15

Sometimes: There are some forms of pulmonary HTN that are inherited and there are some conditions that lead to pul HTN that are inherited but there are also forms of pul HTN that are not inherited.

Answer 16

It may be inherited: Up to 5% of patients with pulmonary arterial hypertension (pah) may have a genetic or heritable cause. Research studies have identified a genetic abnormality affecting bone morphogenetic protein receptor 2 (bmpr2) that appears to predispose a patient to pah. Fortunately, even if an individual inherits the abnormal gene, the likelihood of developing pah is only 1 in 5.

Answer 17

Pulmonary HTN: Yes, there is a category of pulmonary hypertension that is familial. I have reviewed several case reports about this. It does not seem that be that common in every day practice.

Answer 18

Sometimes: It is felt that about 7-10% of patients with the idiopathic form of phtn( what we used to call primary pulmonary hypertension) have a genetic condition predisposing them to develop this disease.

Answer 19

It may be inherited: Up to 5% of patients with pulmonary arterial hypertension (pah) may have a genetic or heritable cause. Research studies have identified a genetic abnormality affecting bone morphogenetic protein receptor 2 (bmpr2) that appears to predispose a patient to pah. Fortunately, even if an individual inherits the abnormal gene, the likelihood of developing pah is only 1 in 5.

is pulmonary hypertension hereditary?

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