A member asked:

Could paxil (paroxetine) and zoloft be taken together?

7 doctors weighed in across 3 answers
Dr. Pamela Pappas answered

Specializes in Psychiatry

Why?: I'm wondering why you'd want to take 2 drugs in the same class? Depending on the doses of each, it could result in serotonin syndrome. I recommend against this.

Answered 11/18/2013

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Yes: Yes, it is possible to take both of them together. However, the overall dose of each should be lowered since they will raise each others blood levels. Also, there remains a rare risk of serotonin syndrome and an increased incidence of difficulty reaching orgasm.

Answered 9/1/2019

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Dr. Alan Ali answered

Specializes in Psychiatry

Paxil/Zoloft: Not advised, since both belong to same group of Antidepressants (SSRIs).

Answered 5/18/2015

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