Is it possible for me to lose weight with lipozene if i take synthroid (thyroxine)?

Yes: Lipozene is a dietary fiber supplement. It can cause mild weight loss because it expands in your stomach and can make you feel full so that you eat less (if you don't eat less you won't lose weight). As long as you take Synthroid (thyroxine) first thing in the morning and wait a few hours before taking the Lipozene, there should be no problem.