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Jackson, MS
A 61-year-old female asked:

Can you take zanaflex (tizanidine) and hydrocodone together?

2 doctor answers4 doctors weighed in
Dr. Ankush Bansal
Internal Medicine 17 years experience
Yes, but...: Be very careful regarding dizziness, sleepiness/lethargy, and breathing. They will act together to increase these risks. And be sure to clear it with your own doctor as to the dose and how often you can do that.
Dr. Brian Nichol
Anesthesiology 30 years experience
Yes: They are often prescribed for concomitant use. Do watch for the side effects of sedation which both may cause in some people.

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Jackson, MS
A 61-year-old female asked:

Can you take hydrocodone and Zanaflex (tizanidine) together?

2 doctor answers3 doctors weighed in
Dr. Clifford Gevirtz
Anesthesiology 40 years experience
Yes: The only real issue is the sedative effects of both. Some people find that individually they are mild but together they make you very very sleepy. Also both can lower blood pressure so be careful when getting up from bed or a chair, you suddenly feel dizzy. This is called ortho static hypotension.

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Last updated Sep 26, 2020

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