HealthTap Online Primary Care Doctors Accepting New Patients
Book a video visit
HealthTap
Telehealth
A member asked:

Can zoloft (sertraline) decrease the effects of adderall? or could i be gaining a tolerance to adderall?

5 doctors weighed in across 2 answers
Dr. Pamela Pappas answered

Specializes in Psychiatry

Not decrease: In some cases zoloft (sertraline) can accentuate -- not decrease -- the effects of stimulants. Please discuss these issues with your psychiatrist.

Dr Fowler agreed

Answered 10/4/2013

4.8k views

Thank
Dr. Heidi Fowler answered

Specializes in Psychiatry

Agree w Dr. Pappas.: Per Drugs.Com drug interaction checker - drug interaction checker > Adderall (amphetamine / dextroamphetamine) plus Zoloft (sertraline) may ^ risk for serotonergic syndrome. May also ^ side effects of nervousness, anxiety, racing thoughts and restlessness. However, it is usually safe together.

Dr Anyanwu and 2 doctors agreed

Answered 3/29/2020

514 views

Thank

Related Questions

A member asked:

Can I take tribulus and fenugreek supplements while taking zoloft (sertraline) and adderall daily ?

A doctor has provided 1 answer

A member asked:

I was diagnosed with PKD recently. I'm on zoloft, (sertraline) adderall, & trazadone. Is it okay for me to be taking all those?

A doctor has provided 1 answer

A member asked:

I am prescribed to 10mg Adderall. Can Adderall cause anxiety/panic attacks? I also take 25mg Zoloft (sertraline) for anxiety

2 doctors weighed in across 2 answers

A member asked:

Is it safe to take folic acid pills with Adderall and zoloft (sertraline)?

A doctor has provided 1 answer

A member asked:

What are the chances i'll gain weight on prozac? Gained weight on Zoloft (sertraline) . I am now also taking Adderall . I'm extremely active and eat healthy as is

A doctor has provided 1 answer

Sponsored Content
HealthTap Medical Group does not endorse products or services. Sponsored content revenues support our mission to make health information free and accessible to all.Learn more

People also searched for:

Can you take Zoloft (sertraline) if you are on adderall?
I took a Zoloft (sertraline) and then adderall, are there any drug interractions?
I have a question , if I took my Zoloft (sertraline) and then I took Adderall is it safe?
Is unisom sleep tabs safe to take with Zoloft (sertraline) and Adderall?
Is qcarbo16 Mega strength safe to drink while on adderall & zoloft (sertraline)? I like to cleanse my body every few months for my athletic training program.

Telemedicine

Primary Care
Manage Your Conditions
Women's Health
Children's Health
Men's Health
Senior Health
Wellness, Prevention & Lifestyle
Sexual Health
Mental & Behavioral Health
Travel Medicine
Urgent Care
Ask your question
Didn't find what you're looking for?

90,000 U.S. doctors in 147 specialties are here to answer your questions or offer you advice, prescriptions, and more.

Ask your question

More of what we treat

Allergies
Antibiotics
Asthma
High Blood Pressure
Prescriptions
Type 2 Diabetes
Content on HealthTap (including answers) should not be used for medical advice, diagnosis, or treatment, and interactions on HealthTap do not create a doctor-patient relationship. Never disregard or delay professional medical advice in person because of anything on HealthTap. Call your doctor or 911 if you think you may have a medical emergency.
HealthTap
HIPAA logo
HIPAASecure
Soc 2 Type 2 logo
SOC 2 Type 2Certified
JCAHO Accredited
JCAHOAccredited
Member App

Download HealthTap

Video visit and message your doctor

Member App QR Code
Play Store Member LinkApp Store Member Link

Questions?

+1 (888) 828-0841support@healthtap.com
LinkedInTwitter
HomeTermsPrivacyCookiesDMCAHealth TopicsDoctors DirectoryDoctor Q&A by Specialty
Copyright 2026 HealthTap, Inc.