Yes: Sudafed and Methadone should be O.K. To take together, even though one is a mild upper and the other is a downer. Sudafed is a mild stimulant that acts as a decongestant and vasoconstrictor of blood vessels. Methadone works primarily by binding to opiate receptors in the brain. This reply is based on the assumption that sudafed is not transformed into an illicit drug by some buyers.
Answered 3/16/2021
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