Is it okay to take sudafed and mucinex (guaifenesin) together?

Yes: This is fine to take together and some companies will package these drugs together into 1 pill. The sudafed is a great decongestant and the Mucinex (guaifenesin) can help break up the mucus in your nose/sinues/lungs. If you have any heart issues or blood pressure issues, you will need to check w/ your doctor 1st before you take the sudafed. Mucinex (guaifenesin) works best when you drink plenty of water.