U.S. doctors online nowAsk doctors free
A 34-year-old member asked:

How do benicar (olmesartan) and lisinopril differ?

2 doctor answers4 doctors weighed in
Dr. Calvin Weisberger
52 years experience
benicar (olmesartan): Benicar (olmesartan) is an angiotensin receptor blocker and Lisinopril is an angiotensin converting enzyme inhibitor. They work in the same pathway but in different places. Their results are similar.
Dr. Alvin Lin
Geriatrics 31 years experience
Dry ticklish cough: As dr. Weisberger noted, Benicar (olmesartan) is an arb while Lisinopril is an ace inhibitor. The latter has a greater risk for dry ticklish cough compared to the former. Otherwise, both are used to lower blood pressure and have been proven beneficial in heart failure as well as protecting kidneys. Cost is the other big difference b/c Benicar (olmesartan) is a brand drug while Lisinopril is a generic available for $4/mo.

Similar questions

A 39-year-old member asked:

Does Benicar (olmesartan) have fewer side effects than lisinopril?

2 doctor answers6 doctors weighed in
Dr. Steven Ajluni
Cardiology 36 years experience
ARB's vs ACEI: Benicar (olmesartan) an arb works similarly in many ways to lisiniopril (acei). They both block at different points in the renin-angiotensin system. A by-product of the acei however is a buildup in a chemical called bradykinin, which can produce throt irritation and a dry cough in 5-10% patients. A cough like this is much less likely with an arb agent like benicar (olmesartan).
A 38-year-old member asked:

Does Benicar (olmesartan) have lesser side effects than lisinopril?

1 doctor answer2 doctors weighed in
Dr. Reginald Gohh
Nephrology and Dialysis 32 years experience
User dependent: Both Benicar (olmesartan) and Lisinopril are used to treat high blood pressure. Both block the effects of angiotension--a hormone that causes constriction of blood vessels and increases blood pressure. Lisinopril has been available for several years and is available as a generic (cheaper) but can cause an annoying cough. Benicar (olmesartan) is a newer drug and is more expensive. Both can cause high potassium levels.
Last updated Aug 23, 2017


Content on HealthTap (including answers) should not be used for medical advice, diagnosis, or treatment, and interactions on HealthTap do not create a doctor-patient relationship. Never disregard or delay professional medical advice in person because of anything on HealthTap. Call your doctor or 911 if you think you may have a medical emergency.