Question 1

will cymbalta (duloxetine) make me feel better right away?

Accepted Answer

No: The effects of Cymbalta (duloxetine) will take from 1 week to 1 month depending on why you are using it.  It can help symptoms of pain in 1-2 weeks, and depression in 1-4 weeks. It usually takes longer for Cymbalta (duloxetine) to help symptoms of anxiety.

Question 2

i wasbumped up to 60 mg of cymbalta two weeks ago. how long before i feel better? have been on it since 2006, went off twice. should it still work?

Accepted Answer

Pain or depression: Why are you on cymbalta? What are the diagnoses? I would consider a second opinion since you have been on it since 2006

without effect.

Question 3

so if cymbalta (duloxetine) takes time to build up in your system then if i was going to have a reaction to it it wouldn't happen right away either?

Accepted Answer

Doesn't really work: That way. Side effects may have rapid onset even though therapeutic effects take longer.

Question 4

if i stop taking cymbalta (duloxetine) immediately, will all the side effects stop right away?

Accepted Answer

Yes: All of the antidepressants can cause withdrawal symptoms. Your body has been used to an increased amount of serotonin and when the medicine is stopped you could experience a lot of different side effects. Sometimes people get headaches, dizziness and nausea. You doctor will often wean you off of this medicine to prevent these symptoms.

Question 5

i am switching from cymbalta to pristiq.  i started on  25 mg pristiq and will go to 50 mg. pristiq. how long after i start 50 mg will i feel better?

Accepted Answer

Pristiq: 50 mg if often an effective dose for Pristiq.  Although there may be some early improvements before this, usually at least several weeks for full effect. Take care.

Question 6

does cymbalta (duloxetine) have to build up in your system if your talking it for joint pain or does it work right away?

Accepted Answer

Not a pain reliever: Cymbalta (duloxetine) is a unique medication for chronic pain.  It increases the serotonin  and norepinephrine between nerve cells.  It does take some time (days-weeks) for this to happen.  It doesn't work like other short-acting pain relievers such as ibuprofen.

Question 7

added 10 mg nortriptyline (nummular headache) to 50 mg trazodone (insomnia) with 60 mg cymbalta (duloxetine) (migraine). felt dizzy, drugged & weak so stopped trazodone. feel better, but can't sleep. what to do?

Accepted Answer

See a Doctor.: Having stopped trazodone just like that will affect your sleep. I recommend to try increase  nortriptyline to 20 mg and see if it helps you sleep better.

Question 8

what is cymbalta (duloxetine)?

Accepted Answer

A multi-use medicine: Duloxetine increases the amount of norepinephrine and serotonin in the tiny space between neurons for a few microseconds.  More importanly for the treatment of depression, is the actual internal response by the cell binding the medication which takes 3-6 weeks or more for full effect.  This medicine is further known to help reduce pain transmission up the spinal cord as well.

Question 9

how does cymbalta (duloxetine) work?

Accepted Answer

Cymbalta (duloxetine): Is an nsri, or a norepinephrine/serotonin reuptake inhibitor.  This means that Cymbalta (duloxetine) slows the breakdown of both of these neurotransmitters, which allows them to have a longer effect.

Question 10

how effective is cymbalta (duloxetine)?

Accepted Answer

Pain/ depression: Cymbalta (duloxetine) is as effective as any other antidepressant. So what makes it special?  Its ability to improve diabetic peripheral neuropathic pain& chronic pain.

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Doctor answers about:

Will Cymbalta make me feel better right away

A member asked:

Will cymbalta (duloxetine) make me feel better right away?

A member asked:

I wasbumped up to 60 mg of cymbalta two weeks ago. how long before i feel better? have been on it since 2006, went off twice. should it still work?

A member asked:

So if cymbalta (duloxetine) takes time to build up in your system then if i was going to have a reaction to it it wouldn't happen right away either?

A member asked:

If i stop taking cymbalta (duloxetine) immediately, will all the side effects stop right away?

A member asked:

I am switching from cymbalta to pristiq. i started on 25 mg pristiq and will go to 50 mg. pristiq. how long after i start 50 mg will i feel better?

A member asked:

Does cymbalta (duloxetine) have to build up in your system if your talking it for joint pain or does it work right away?

A member asked:

Added 10 mg nortriptyline (nummular headache) to 50 mg trazodone (insomnia) with 60 mg cymbalta (duloxetine) (migraine). felt dizzy, drugged & weak so stopped trazodone. feel better, but can't sleep. what to do?

A member asked:

What is cymbalta (duloxetine)?

A member asked:

How does cymbalta (duloxetine) work?

A member asked:

How effective is cymbalta (duloxetine)?

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