Question 1

what is the use of spironolactone?

Accepted Answer

Many uses: Spironolactone is a diuretic and can be used to get rid of the body's extra fluid.  It's also a aldosterone blocker and can be used to block the adverse effects of aldosterone on the heart and other tissues.  It's also a testosterone blocker and can be used to decrease hair growth in patients with excessive hair.

Question 2

is taking 100mg of spironolactone the right dosage?

Accepted Answer

Depends: It depends on why one is on spirolonolactone.  The usual dose for treatment of hypertension is 12.5 - 50 mg daily dose.  At times, up to 200 mg per day can be used in treating edema.

Question 3

could the midicine aldactone (spironolactone) affect progestrone levels?

Accepted Answer

Not that I'm aware: Hi. Spironolactone (Aldactone) blocks the aldosterone and testosterone receptors, but I'm not aware of any inhibition of the Progesterone receptor.

Question 4

which is better spironolactone or flutamide and why?

Accepted Answer

Better/worse: I suppose you could get many opinions on this. Spironolactone has been around forever, very inexpensive and safe; Flutamide is newer, somewhat more effective, and expensive. For women wanting or at-risk to get pregnant neither is good, but spironolactone may be safer if you conceicve unexpectedly.

Question 5

does spironolactone block testosterone?

Accepted Answer

Not really: Spironolactone is an old, commonly used (but not really effective) diuretic that has an interesting side effect: its chemical structure is similar enough to block testosterone receptors in the face and scalp, and helps to decrease acne, oily skin, and facial hair growth.

Question 6

can spironolactone cause pregnancy mask?

Accepted Answer

Don't believe so: Hi. I'm not a gyn, but I use a fair amount of spironolactone, and I've never heard of it causing melasma (mask of pregnancy). I hope some gyn will correct me if I'm wrong.

Question 7

is spironolactone a testosterone blocker?

Accepted Answer

Yes: Spironolactone both blocks the androgen receptor (for testosterone) and lowers testosterone production.

Question 8

does spironolactone lower testosterone in men?

Accepted Answer

Probably yes...: Most of the studies done seem to deal with females with high testosterone levels, but i would assume the same biochemical pathways would be applicable to males. If you are worried about total and free testosterone levels as a male, as well as serum estradiol, you may want to avoid this medication. Some of its effect may center around an increase in shbg or TBG which decreases free testosterone.

Question 9

can spironolactone cause menstrual like cramps?

Accepted Answer

Probably not: Usually spironolactone is very well tolerated and can be used short term for premenstrual fluid retention. There is a risk of elevated potassium levels so they may need to be monitored.

Question 10

can spironolactone cause melasma or make it worse?

Accepted Answer

Not known: Melasma can worsen due to estrogen, progesterone, sun exposure, etc. Spironolactone can lower testosterone, so in theory it could increase estrogen slightly, but have never seen it described as causing or worsening melasma.

Get Virtual Care

For Businesses

About Us

HealthTap Online Primary Care Doctors Accepting New Patients

Doctor answers about:

What is spironolactone allergy

A member asked:

What is the use of spironolactone?

A member asked:

Is taking 100mg of spironolactone the right dosage?

A member asked:

Could the midicine aldactone (spironolactone) affect progestrone levels?

A member asked:

Which is better spironolactone or flutamide and why?

A member asked:

Does spironolactone block testosterone?

A member asked:

Can spironolactone cause pregnancy mask?

A member asked:

Is spironolactone a testosterone blocker?

A member asked:

Does spironolactone lower testosterone in men?

A member asked:

Can spironolactone cause menstrual like cramps?

A member asked:

Can spironolactone cause melasma or make it worse?

HealthTap Online Primary Care Doctors Accepting New Patients

Telemedicine

Primary Care

Manage Your Conditions

Women's Health

Children's Health

Men's Health

Senior Health

Wellness, Prevention & Lifestyle

Sexual Health

Mental & Behavioral Health

Travel Medicine

Urgent Care

Didn't find what you're looking for?

More of what we treat

Allergies

Antibiotics

Asthma

High Blood Pressure

Prescriptions

Type 2 Diabetes

For Businesses

Company

Health Content

Join Us

Download HealthTap

Questions?