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A member asked:
Can spironolactone cause melasma or make it worse?
A doctor has provided 1 answer
Not known: Melasma can worsen due to estrogen, progesterone, sun exposure, etc. Spironolactone can lower testosterone, so in theory it could increase estrogen slightly, but have never seen it described as causing or worsening melasma.
Answered 12/26/2022
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