Question 1

had stuffy nose faint sense smell bone marrow biopsy in august now nostril passage feel heavy difficulty breathing ct scan showed nothing other tests?

Accepted Answer

Almost understand: The question is a bit choppy and I struggle to see how the bone marrow biopsy fits in with the rest.  Was the CT scan of the sinus?  Stuffy nose, loss of sense of smell, congestion and difficulty breathing make me think of rhinitis, which can be caused by inhaled allergens or irritants among other causes. An Allergist can best determine cause and optimize treatment.

Question 2

why do i  black spots in my skull. revealed by a cat scan. bone marrow biopsy revealed no cancer?

Accepted Answer

DDx: I see a lot of multiple myeloma, so i think of lytic (punched out) lesions in the skull (calvarium) as myeloma. However other cancers such as squamous cell cancers (head/neck, lung, etc) can produce lytic lesions. Sometimes veins going through bone can produce "holes" that are normal. The differential diangosis (ddx) is broad -- eg http://www.Calvariallesions.Com/index.Html.

Question 3

have aps  , does it cause high b2m ? normal ct/pet and bone marrow biopsy.high ldh,spleenomegaly, normal spep,night sweat, tired, low platelete& rbc

Accepted Answer

Not necessarily: The B2M protein is "non-specific: and not necessarily associated with APS I am going to refer your question to one of our HEMATOLOGY/ONCOLOGY experts. This referral should not frighten you! It is simply to help you find out more about  your clinical situation.
Hope this helps
Dr Z

Question 4

could a pelvic mri tell if you have had a bone marrow biopsy?

Accepted Answer

Not Really: Shortly after the biopsy there will be some acute changes on the mri, but it would probably be hard to tell if these changes are due to a biopsy or something else.  After some time passes, you would be unable to tell.

Question 5

could splenic lymphoma exist  even with negative bone marrow biopsy & negative pet/ct , but splenomegaly  occur? other causes has ruled out.

Accepted Answer

Yes/No: Lymphoma can ,on rare occasions, involve spleen alone, sparing all other organs. But PET will show increased uptake(high SUV) and CT would show enlargement of Spleen.
So depending on your symptoms and the degree of enlargment of your spleen, your doctor may, somewhere along the line, consider removal of the spleen(splenectomy). But this step would only be taken if your spleen is causing U any harm

Question 6

is there any condition that could cause both neutropenia and hypothyroidism? all orderedblood tests and bone marrow biopsy came back normal/negative.

Accepted Answer

Unrelated: Hypothyroidism is very common condition, so it is not uncommon to have other conditions that can coexist independent of each other. Neutropenia is often caused by bone marrow damage of some kind or other, although on rare occasions it can be congenital(since birth, cause unknown). The degree of neutropenia matters. So you should give us all the numbers of your CBC...such as WBC count &amp; Neutrrophil

Question 7

i have sjgren's synd yrs ago the ct &mri showed diffused bone marrow, but the marrow biopsy was ok.now i'm ill ,weight loss &no energy. what do i do?

Accepted Answer

Sjogrens: It is difficult to say in one paragraph as there are so many variables involved with connective tissues disease.  Routine blood work and physical examination are important to ensure you don`t have inflammation or organ dysfunction in other areas of your body.  If you are taking medication then you could also be suffering from side effects.  A normal BM biopsy is encouraging.  Hang in there!

Question 8

if blood work has not shown the cause of my polycythemia, will a bone marrow biopsy be helpful? my hematologist has mentioned it, but not done it.

Accepted Answer

It may or maynot: The diagnosis of polycythemia requires several criteria which are well defined. They include CBC, Hb level, WBC level, platelets and Blood erythropoetin level. Send us the results and we can help you. Unless your Hb is above 17 grams, you can get a follow up CBC in 2-3 months and see if it is rising.

Question 9

can any doc tell me what's meant when a bone marrow biopsy/aspiration report shows hypocellular marrow?

Accepted Answer

Bone marrow: Bone marrow cellularity refers to how much of the marrow is making blood cells, and how much is fat. As people age, it tends to decline and move more centrally. Severe hypocellularity may indicate aplastic anemia or even leukemia, which needs treatment. Lesser degrees may or may not, depending on other symptoms and lab findings.

Question 10

if you have chronic anemia and doctors can't find the cause, is it common to get a bone marrow biopsy?

Accepted Answer

Chronic anemia: Not uncommon, in normocytic anemia  if they want to see how the cells are generating  RBC, whether it is making  cells or not making cells.  Have you also been tested  for celiac disease, thyroid disease G6PD,  and medications  that can sometimes cause anemia  as well? .

http://www.aafp.org/afp/2000/1115/p2255.html

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Doctor answers about:

What does abnormal bone marrow signals on a lower back mri mean and why do I have to have a CT scan and a bone marrow biopsy

A member asked:

Had stuffy nose faint sense smell bone marrow biopsy in august now nostril passage feel heavy difficulty breathing ct scan showed nothing other tests?

A member asked:

Why do i black spots in my skull. revealed by a cat scan. bone marrow biopsy revealed no cancer?

A member asked:

Have aps , does it cause high b2m ? normal ct/pet and bone marrow biopsy.high ldh,spleenomegaly, normal spep,night sweat, tired, low platelete& rbc

A member asked:

Could a pelvic mri tell if you have had a bone marrow biopsy?

A member asked:

Could splenic lymphoma exist even with negative bone marrow biopsy & negative pet/ct , but splenomegaly occur? other causes has ruled out.

A member asked:

Is there any condition that could cause both neutropenia and hypothyroidism? all orderedblood tests and bone marrow biopsy came back normal/negative.

A member asked:

I have sjgren's synd yrs ago the ct &mri showed diffused bone marrow, but the marrow biopsy was ok.now i'm ill ,weight loss &no energy. what do i do?

A member asked:

If blood work has not shown the cause of my polycythemia, will a bone marrow biopsy be helpful? my hematologist has mentioned it, but not done it.

A member asked:

Can any doc tell me what's meant when a bone marrow biopsy/aspiration report shows hypocellular marrow?

A member asked:

If you have chronic anemia and doctors can't find the cause, is it common to get a bone marrow biopsy?

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