Question 1

had a lupus anticoagulant test done all was normal except for a high thrombin time at 22.8 is this serious? factor 5 also runs in my family.

Accepted Answer

Normally:  a factor V  deficiency can cause a prolonged thrombin time But your bleeding time and platelet count should be unaffected. Certain medications and other diseases could also cause elevated thrombin time.

Question 2

can you explain what a positive test for lupus anticoagulant means?

Accepted Answer

Autoantibodies.: Your body is producing antibodies directed against its own tissues and is likely at increased risk for the development of an autoimmune disease such as lupus erythematosus, rheumatoid arthritis, thyroiditis, vitiligo, infammatory bowel dis or pernicious anemia from gastritis. Lac can cause clotting disorders and miscariages, but is not in and of itself an important predictor of clinical outcomes.

Question 3

what is the significance of a positive test for  lupus anticoagulant?

Accepted Answer

Autoantibodies.: Your body is producing antibodies directed against its own tissues and is likely at increased risk for the development of an autoimmune disease such as lupus erythematosus, rheumatoid arthritis, thyroiditis, vitiligo, infammatory bowel dis or pernicious anemia from gastritis. Lac can cause clotting disorders and miscariages, but is not in and of itself an important predictor of clinical outcomes.

Question 4

in 11/2014 i was hospitalized with bilateral pe.  3 lupus anticoagulant tests have come back positive, and he said it's primary.  does that mean aps?

Accepted Answer

Almost...: In my experience it can be primary, but other autoimmune disease must be excluded. IgM, followed by IgG anti -cardiolipin  antibodies are the most problematic!  This is important, since apart from anticoagulants, other drugs may be needed.

Question 5

what do these mean? lupus anticoagulant weakly present at 1.30; positive ana test 1:40 speckled pattern; negative anticardioliptin and beta2

Accepted Answer

Not much: A weakly present lupus anticoagulant and an ANA of 1:40 are common in the general population, and usually  not an indication of an autoimmune disorder. You should visit with the physician who ordered these tests to review them with you however. A test alone does not give any answers. Doctors will need both a patient's history and tests to determine  further management.

Question 6

my ana test came back positive. 
lupus anticoagulant positive. 
lyme test igg test positive for 18kda, 41 kda, 58 kda. flagged as abnormal but was told not positive for lyme. 
what does all this mean? 
do i have lupus? ra....

Accepted Answer

Hi there : I’m sorry to hear that you are worried, we can’t diagnose something without having your full medical history and without a clinical exam, please take those tests results to the doctor who order them and ask him/her about everything that worries you, until then, stay calm and trust your doctor.

No more dr google please :)

Question 7

a lupus anticoagulant is detected since one of the two confirmatory tests is positive.hexagonal phase confirm -positive - what does it mean? also high alpha-1, low albumin, high alkaline phosphate, crp lvl 31, high absolute neutros,lymphocs,eosinos

Accepted Answer

Lab tests: Please ask the physician that ordered them to explain the results to you as the lab results should only be used in conjunction withe the history and physical examination. Good Luck

Question 8

do all people diagnosed with the disease lupus test positive for the lupus anticoagulant?

Accepted Answer

Most, not all.: Lac is common in sle, but not universal.

Question 9

can all people diagnosed with the disease lupus test positive to lupus anticoagulant as well?

Accepted Answer

Not necessarily: This can be seen in the setting of lupus but with other autoimmune diseases as well as some patients can positive for it and not have any associated diseases with it.

Question 10

what does it mean if im positive for beta 2 glycoproteins, but not for lupus anticoagulant or cardiolipins? no history of bloodclots or miscarriage.

Accepted Answer

See details: It depends on the the exact level of the beta-2. Low levels are not significant. It is unusual to be cardiolipin negative but beta-2 positive but it can occur.

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Doctor answers about:

What does a positive lupus anticoagulant test mean

A member asked:

Had a lupus anticoagulant test done all was normal except for a high thrombin time at 22.8 is this serious? factor 5 also runs in my family.

A member asked:

Can you explain what a positive test for lupus anticoagulant means?

A member asked:

What is the significance of a positive test for lupus anticoagulant?

A member asked:

In 11/2014 i was hospitalized with bilateral pe. 3 lupus anticoagulant tests have come back positive, and he said it's primary. does that mean aps?

A member asked:

What do these mean? lupus anticoagulant weakly present at 1.30; positive ana test 1:40 speckled pattern; negative anticardioliptin and beta2

A member asked:

My ana test came back positive. lupus anticoagulant positive. lyme test igg test positive for 18kda, 41 kda, 58 kda. flagged as abnormal but was told not positive for lyme. what does all this mean? do i have lupus? ra....

A member asked:

A lupus anticoagulant is detected since one of the two confirmatory tests is positive.hexagonal phase confirm -positive - what does it mean? also high alpha-1, low albumin, high alkaline phosphate, crp lvl 31, high absolute neutros,lymphocs,eosinos

A member asked:

Do all people diagnosed with the disease lupus test positive for the lupus anticoagulant?

A member asked:

Can all people diagnosed with the disease lupus test positive to lupus anticoagulant as well?

A member asked:

What does it mean if im positive for beta 2 glycoproteins, but not for lupus anticoagulant or cardiolipins? no history of bloodclots or miscarriage.

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