Question 1

extensive tumor necrosis! how to diagnose, what to do?

Accepted Answer

Remove if possible: When tumor get very large and essentially loose blood supply necrosis can set in.  If extensive, tumor necrosis syndrome develops and release of toxins into the blood stream can occur.  At this point debulking of the lesion is beneficial.

Question 2

what can you tell me about the tumor necrosis factor?

Accepted Answer

Cytokine: Tumor necrosis factor was a cytokine first isolated from macrophages and CD4 cells in response to understanding how Coley's toxin worked.  It was felt to be the factor that induced destruction of malignancies but when sequenced proved to be the same molecule as cachexin, a chemical produced by tumor like pancreatic cancer that induced cachexia in patients.

Question 3

what is the tumor necrosis factor alpha?

Accepted Answer

Stimulate reaction: Tumor necrosis-alpha , ( tnf) also known as cachexin or cachectin is a cytokine mainly secreated  by macrophages stimulates the acute phase of inflamation. Tnf regulates the immune cells, performs varieties  functions  as pyrogen ( causing  fever ), regulates cell proliferation, differentiation, apoptosis ( cell death or suicide ) , in lipid metabolism, in coagulation of blood  etc.

Question 4

what is human tumor necrosis factor alpha and why is its use?

Accepted Answer

Stimulate reaction: Tumor necrosis-alpha , ( tnf) also known as cachexin or cachectin is a cytokine mainly secreated  by macrophages stimulates the acute phase of inflamation. Tnf regulates the immune cells, performs varieties  functions  as pyrogen ( causing  fever ), regulates cell proliferation, differentiation, apoptosis ( cell death or suicide ) , in lipid metabolism, in coagulation of blood  etc.

Question 5

what is human tumor necrosis factor alpha? why is it so painful?

Accepted Answer

Endogenous pyrogen: In looking for mechanisms for Coleys Toxin as a cancer vaccine,  bacterial toxins used were found to  release a chemical termed tumor necrosis factor. This was found to be the same as  cachexin,  or now TNFα  It is   involved in systemic inflammation and is a member of a group of cytokines that stimulate  acute phase reaction. It is produced  by macrophages, CD4+ lymphocytes and NK cells.

Question 6

what is the definition or description of: tumor necrosis factor-alpha?

Accepted Answer

A cytokine: Tnf Alpha is a protein molecule involved in communication between cells, it is involved in inflammation. The main function is part of the immune system response.  It is primarily produced by cells called macrophages but may be produced by many other cells.  It causes fever, may induce programmed cell death (apoptosis) and is important in the response to sepsis (via molecules called interleukins).

Question 7

what are those tumor necrosis factor-alpha blockers?

Accepted Answer

Tnf blocker: Tumor necrosis factor (tnf) promotes the inflammatory response and is increased in autoimmune disorders such as rheumatoid arthritis, ankylosing spondylitis, crohn's disease, psoriasis and hidradenitis suppurativa. The various tnf blockers help treat these conditions.

Question 8

how would you describe tumor necrosis factor-alpha blockers?

Accepted Answer

Tumor necrosis: Factor (tnf) promotes the inflammatory response, which in turn causes many of the clinical problems associated with autoimmune disorders such as rheumatoid arthritis, ankylosing spondylitis. These disorders are sometimes treated by using a tnf inhibitor. The important side effects that have been most extensively related to tnf blockers include: lymphoma, infections, congestive heart ad others.

Question 9

what is tumor necrosis factor alpha? it sounds like it makes something die?

Accepted Answer

Immunology: Tumor necrosis factor Alpha is an inflammatory immune chemical marker that is used in research for new medicines to treat such problems as multiple sclerosis and even alzheimers.  Several other chemicals include interleukins and cytokines.  The names are catchy, and come from research discoveries, but do not really correlate with survival.

Question 10

what is human tumor necrosis factor tnf alpha and why is it so painful?

Accepted Answer

Does the term: Inflammatory cytokine help? It is not specific to any disease but may be a pathway to appetite loss, it's also called cachexin, and a pathway involved in cellular and organ injury...Including radiation, and possibly a cause of lung injury from xrt.  It is not of itself painful.

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Doctor answers about:

Tumor necrosis facto

A member asked:

Extensive tumor necrosis! how to diagnose, what to do?

A member asked:

What can you tell me about the tumor necrosis factor?

A member asked:

What is the tumor necrosis factor alpha?

A member asked:

What is human tumor necrosis factor alpha and why is its use?

A member asked:

What is human tumor necrosis factor alpha? why is it so painful?

A member asked:

What is the definition or description of: tumor necrosis factor-alpha?

A member asked:

What are those tumor necrosis factor-alpha blockers?

A member asked:

How would you describe tumor necrosis factor-alpha blockers?

A member asked:

What is tumor necrosis factor alpha? it sounds like it makes something die?

A member asked:

What is human tumor necrosis factor tnf alpha and why is it so painful?

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