Question 1

what is the her2- positive breast cancer survival rate?

Accepted Answer

Very high!: The five year survival rate for all breast cancer is over 90%. Her2+ cancers used to have the worst prognosis, but Herceptin (trastuzumab) changed that. Now they have a very good prognosis if they are caught at an early stage (stage 1 or 2). The stage really determines the prognosis, so without that information i can't give you a number. But I am happy for my patients with a her2+ cancer-- many  treatments!

Question 2

what is the survival rate for breast cancer stage 3c? right breast mastectomy done with auxillary clearance. er/pr is +ve and her2 is -ve. suggested with 6 rounds chemo and radiation therapy.

Accepted Answer

Generally speaking : Stage 3 ten year overall survival is about 60%.

Question 3

her2-positive breast cancer stage 1 level 3 and 70 yrs old - how much longer can somebody expect to live?

Accepted Answer

A full lifetime: Stage 1 cancer is curable with appropriate treatment. With surgery to remove the tumor, and appropriate chemotherapy including herceptin, (trastuzumab) the chance of cure is very high.  In someone age 70, the doses of chemo drugs might need to be reduced, but Herceptin (trastuzumab) is not chemo. Older people do well on it!  it is very unlikely she will die from breast cancer if she gets good treatment now.

Question 4

what are the odds of having stage 2b invasive ductal carcinoma her2 positive breast cancer and papillary thyroid cancer at age 40?

Accepted Answer

Odds are low.: But it is still possible to have both.  Risk of having papillary thyroid before forty is about 13/100,000. Risk of having breast Ca is about 11/100,000.  The overlap of the two independent events  is slightly less than 1 in a million.

Question 5

is her2 better if negative or positive in regards to breast cancer?

Accepted Answer

Better.: HER2 receptor testing (along with estrogen and progesterone receptor testing) is done on breast cancer tissue to help guide the oncologist for endocrine chemotherapy. It's better if tissues are positive in each case as this increases the treatment choices. If all three are negative (triple negative breast cancer), the prognosis for cure is diminished.

Question 6

what do er and her2 positive mean in relation to breast cancer?

Accepted Answer

See below: Estrogen receptor (er) is measured to determine whether a tumor is sensitive to hormonal manipulation (things like tamoxifem, arimidex, or removal of ovaries - depending on your age and other factors.  Er+ tumors have better prognosis.  In general her2 + tumors have a worse prognosis, but these tumors may respond to Herceptin (trastuzumab) or similar drugs.

Question 7

which is easier to cure a breast cancer who is a pr/er positive and her2 negative or er/pr negative and her2 positive? who has longer prognosis?

Accepted Answer

Er/pr positive: The survival and outcomes are better with receptor positive breast cancer. Stage for stage the long term prognosis is better for this group.
Although Herceptin (trastuzumab) has done a lot for women with her-2 positive disease, it is still a less positive outcome than er pr positive cases.

Question 8

i am 71.  at age 62 i had her2 positive and er positive breast cancer with 6 positive nodes out of 16, .  what are the odds of return of breast cancer?

Accepted Answer

Double-edged Sword: It is hard to give you a number under any circumstance, but especially without the knowledge of your treatment. As you probably learned 9 years ago, women with 4 or more lns involved and her2/neu(+) disease are at high risk for recurrence. Nevertheless, recurrences in her2/neu patients tend to occur within the first 5-10 years. So, at 9yrs we should be optimistic that you will continue to do well.

Question 9

anyone have stage 1 breast cancer with her2/neu positive er/pr negative?

Accepted Answer

Not Uncommon: In general, women w/stage i breast cancer have an excellent prognosis; however, this particular "mix" of receptors can be more aggressive.   If the tumor is <0.6cm (t1a), no additional rx is recommended.  If the tumor is >1cm (t1c), adjuvant chemo w/herceptin is recommended.  For t1b tumors (0.6-1cm), chemotherapy should be considered, weighing in other factors such as pt age and health.

Question 10

im a breast cancer positive, stage 1 with her2 positive, is completly necesary the chemotherapy in my case?

Accepted Answer

Breast CA: It really depends on your risk factors and tumor characteristics. You should have a through consultation with a medical oncologist to determine the best course.

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Doctor answers about:

Survival rates for her2 positive breast cancer

A member asked:

What is the her2- positive breast cancer survival rate?

A member asked:

What is the survival rate for breast cancer stage 3c? right breast mastectomy done with auxillary clearance. er/pr is +ve and her2 is -ve. suggested with 6 rounds chemo and radiation therapy.

A member asked:

Her2-positive breast cancer stage 1 level 3 and 70 yrs old - how much longer can somebody expect to live?

A member asked:

What are the odds of having stage 2b invasive ductal carcinoma her2 positive breast cancer and papillary thyroid cancer at age 40?

A member asked:

Is her2 better if negative or positive in regards to breast cancer?

A member asked:

What do er and her2 positive mean in relation to breast cancer?

A member asked:

Which is easier to cure a breast cancer who is a pr/er positive and her2 negative or er/pr negative and her2 positive? who has longer prognosis?

A member asked:

I am 71. at age 62 i had her2 positive and er positive breast cancer with 6 positive nodes out of 16, . what are the odds of return of breast cancer?

A member asked:

Anyone have stage 1 breast cancer with her2/neu positive er/pr negative?

A member asked:

Im a breast cancer positive, stage 1 with her2 positive, is completly necesary the chemotherapy in my case?

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