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A member asked:
What do er and her2 positive mean in relation to breast cancer?
5 doctors weighed in across 2 answers
See below: Estrogen receptor (er) is measured to determine whether a tumor is sensitive to hormonal manipulation (things like tamoxifem, arimidex, or removal of ovaries - depending on your age and other factors. Er+ tumors have better prognosis. In general her2 + tumors have a worse prognosis, but these tumors may respond to Herceptin (trastuzumab) or similar drugs.
Answered 5/7/2017
5.5k views
Receptor Status: The er positive refers to the receptor status of the breast cancer. This means that the tumor has receptors to estrogen and that anti-estrogen therapy can be used to slow the growth of the tumor. Her2 is a another receptor that is a target of a chemotherapeutic agent called herceptin (trastuzumab).
Answered 9/26/2020
5.5k views
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