Question 1

my last bloidwork showed smudge cells. i know cll is a possibility. is all also a possibility? what elae can cause smudge cells?

Accepted Answer

Not of diagnostic va: Not of clear value. If your CBC is otherwise normal then smudge cells can be ignored. By themselves alone they are do not imply a diagnosis of cll or all. Tell us the results of your CBC and differential counts so that we can be more accurate in informing you what it all means.

Question 2

my last bloodwork showed smudge cells. what percent of people with smudge cells actually have cll?

Accepted Answer

Can&#x27;t be answered: How many healthy people get smudge cells depends mostly on how rough the technician is while preparing the smear, and how eager to call a few broken lymphocytes &quot;smudge cells.&quot; if your absolute lymphocyte count is not way-high and you&#x27;re not anemic and feel well, stop worrying.

Question 3

i have 27 smudge cells out of 100. how likely is it cll?

Accepted Answer

: All laboratory results need to be interpreted in the clinical context and the doctor who ordered the tests is usually in the best position to do that. Talk to the doctor who ordered the tests. Having said that, what is your total lymphocyte count Smudge cells could be due to faulty technique in making a smear.    
Wish you good health!

Question 4

are there causes for smudge cells and high wbc other than cll?

Accepted Answer

Yes.: Smudge cells are cells that are extremely fragile and easy to disrupt the cell membrane when making a blood smear.  Therefore, if the cell is disrupted it can be very hard to identify what kind of cell it is.  The most common and well known disease with smudge cells is cll.  However, many other hematologic diseases also have smudge cells.  Further testing is needed to be sure what cells are there.

Question 5

my wife just had an exam and had a wbc of 16, 000 with numerous smudge cells.  she is 47 and had no swelling of any kind.  is this necessarily cll?

Accepted Answer

It can be: You should definitely discuss this with your wife and with her doctor.  Usually smudge cells are indicative of something like a leukemia and warrant follow up with her doctor and probably a blood specialist.

Question 6

8yr old, diarrhea 1 week.blood test with diff. all in the normal range except for few react. lyphocytes & few smudge cells. what does it mean?cll/all?

Accepted Answer

No: probably diarrhea and reactive lymphocyte are secondary to viral infection  ,he need follow up with his doctor.

Question 7

i was diagnosed with cll 10 years ago, two years ago my white cell count rose to 84.  over the last 2 years it has come down to 54.  what does this mean?

Accepted Answer

Need information: In CLL, there is an overgrowth of lymphocytes which do not function normally against infection.  Normal counts are 4 to 11 K/mcl, so both 84 and 54 are very elevated.  The drop in count could suggest that the disease is improved, but one needs to also consider the anemia and platelet counts, a person's energy level, weight loss, night sweats,  and signs of infection to draw conclusion.

Question 8

could it be cll 7mo f wbc 10.4, neu% 21.6, lym% 76.1, lym# 7.9, mon#0, 2 days prior wbc 7.3 manual diff lymphs 89, 17 smudge, segs3,bands1,mon6. help.

Accepted Answer

Smudge cells: Upon examination of the peripheral blood smear in patients with chronic lymphocytic leukemia (CLL), mature-appearing small lymphocytes may account for 50 to 100 percent of the leukocytes.

Question 9

what do you suggest if my doctor says i don't have cll but hairy cell leukemia?

Accepted Answer

Consult: Nowadays, every leukemia is typed by flow cytometry. Get with the laboratory and a hematologist who's at a major center. Hairy cell is extremely manageable nowadays.

Question 10

my white blood cell counts have been
14
16
most recent 14.7

lymphocytes
4014
5000
most recent  3900

granulocytes
10.1
most recent 9.2

what are the blood levels for diagnosing cll?

my dr says i could have or develop cll

thank you?

Accepted Answer

: To diagnose CLL or chronic lymphoid. Leukemia an indolent B cell lymphocyte increase 
Greater than 5000 absolute lymphs my be used as criteria together with monoclonal B cell fingerprint by using flow cytometry in the same blood specimen

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Doctor answers about:

Smudge cells cll

A member asked:

My last bloidwork showed smudge cells. i know cll is a possibility. is all also a possibility? what elae can cause smudge cells?

A member asked:

My last bloodwork showed smudge cells. what percent of people with smudge cells actually have cll?

A member asked:

I have 27 smudge cells out of 100. how likely is it cll?

A member asked:

Are there causes for smudge cells and high wbc other than cll?

A member asked:

My wife just had an exam and had a wbc of 16, 000 with numerous smudge cells. she is 47 and had no swelling of any kind. is this necessarily cll?

A member asked:

8yr old, diarrhea 1 week.blood test with diff. all in the normal range except for few react. lyphocytes & few smudge cells. what does it mean?cll/all?

A member asked:

I was diagnosed with cll 10 years ago, two years ago my white cell count rose to 84. over the last 2 years it has come down to 54. what does this mean?

A member asked:

Could it be cll 7mo f wbc 10.4, neu% 21.6, lym% 76.1, lym# 7.9, mon#0, 2 days prior wbc 7.3 manual diff lymphs 89, 17 smudge, segs3,bands1,mon6. help.

A member asked:

What do you suggest if my doctor says i don't have cll but hairy cell leukemia?

A member asked:

My white blood cell counts have been 14 16 most recent 14.7 lymphocytes 4014 5000 most recent 3900 granulocytes 10.1 most recent 9.2 what are the blood levels for diagnosing cll? my dr says i could have or develop cll thank you?

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