Question 1

what are the real symptoms of myeloproliferative disorders?

Accepted Answer

Varaible: There are 3 main types- essential thrombocytosis (et), polycythemia vera (pv) and myelofibrosis (mf). In et, there is increased clotting and risk for strokes. In pv, there is generalized itchiness, ruddy face, and stroke risk. In mf, patients get low blood counts over time causing fatigue, large spleen, poor appetite, abdomen pain, transfusion need.

Question 2

what is the definition or description of: myeloproliferative disorders?

Accepted Answer

See below: You may consult this site for info on this topic: http://www.umm.edu/health/medical/altmed/condition/myeloproliferative-disorders

Question 3

i would appreciate some clarity on an important matter.  are myelodsyplastic and myeloproliferative disorders pre-malignant conditions or are they malignancies by their very nature even before an acute transformation has occurred?

Accepted Answer

: They can be but only time will tell. Some genes can be checked as well. Don’t know if they do them down  under?

Question 4

can a thrombocytosis of 425 be myeloproliferative disorders,?

Accepted Answer

: Such a value is not diagnostic, nor does it rule out a myeloproliferative disorder. Borderline high, such values should be interpreted carefully in proper clinical context and dynamics, your doc remains your best resource going forward.

Question 5

could you please tell me whether there any hematologic malignancies in addition to or other than the myeloproliferative disorders/neoplasms?  if so, are any of them common?

Accepted Answer

: This will provide a starting point on information about hematological malignancies; https://www.ons.org/sites/default/files/publication_pdfs/HM%20Ch%20%201.pdf

Question 6

could you please tell me whether a myeloproliferative disorder is the same thing as a myeloproliferative neoplasm?

Accepted Answer

Yes, about same: These terms indicate excess production of blood cells and encompass several conditions, such as  CML, Myelofibrosis and Polycythemia vera.

Question 7

can myeloproliferative disorder be diagnosed by an mri?

Accepted Answer

Myeloid and: Lymphoid refer to blood and marrow elements. Mri cannot greatly help, but can show marrow signal abnormalities. A bone marrow follows evaluation of a smear to discern type and yes no to  leukemia, imaging not in the line up unless symptom point to a bone, .

Question 8

are all acute transformations rare or is there good evidence that the probability of such an occurrence depends upon the particular type of underlying myeloproliferative disorder that a person has?  i'm told that there is more than one type of md.

Accepted Answer

Depends: On the type of myeloproliferative disorder, highest transformation risk being seen in CML, up to 90% in some studies for refractory cases and as low as 10 % in polycythemia Vera or 5% in essential thrombocythemia.

Question 9

what does  myeloproliferative disorder with essential thrombocythemia mean?

Accepted Answer

Too many platelets: The myeloproliferative neoplasms (mpns) involve terminal myeloid cell expansion in the peripheral blood, resulting in various combinations of erythrocytosis (rbc's), leukocytosis (wbc's), thrombocytosis (platelets), bone marrow hypercellularity/fibrosis, and splenomegaly (enlarged spleen). Essential thrombocythemia is a diagnosis of exclusion, made when other forms of mpn are ruled out.

Question 10

what is a myeloproliferative disorder that includes essential thrombocythemia?

Accepted Answer

Too many platelets: Myeloproliferative disorders are a set of marrow malignancies characterized by excessive production of certain types of blood cells. Essential thrombocytopenia is one of them, in which marrow makes too many platelets. There are well-tolerated oral agents which help. Other myelodysplastic syndromes are polycythemia vera and chronic myelogenous leukemia.

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Doctor answers about:

Myeloproliferative disorders medication

A member asked:

What are the real symptoms of myeloproliferative disorders?

A member asked:

What is the definition or description of: myeloproliferative disorders?

A member asked:

I would appreciate some clarity on an important matter. are myelodsyplastic and myeloproliferative disorders pre-malignant conditions or are they malignancies by their very nature even before an acute transformation has occurred?

A member asked:

Can a thrombocytosis of 425 be myeloproliferative disorders,?

A member asked:

Could you please tell me whether there any hematologic malignancies in addition to or other than the myeloproliferative disorders/neoplasms? if so, are any of them common?

A member asked:

Could you please tell me whether a myeloproliferative disorder is the same thing as a myeloproliferative neoplasm?

A member asked:

Can myeloproliferative disorder be diagnosed by an mri?

A member asked:

Are all acute transformations rare or is there good evidence that the probability of such an occurrence depends upon the particular type of underlying myeloproliferative disorder that a person has? i'm told that there is more than one type of md.

A member asked:

What does myeloproliferative disorder with essential thrombocythemia mean?

A member asked:

What is a myeloproliferative disorder that includes essential thrombocythemia?

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