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Is it safe to take duloxetine and sertraline together

A 44-year-old female asked:
Dr. Humberto Quintana
Psychiatry 44 years experience
No not good idea: Cymbalta contains duloxetine and zoloft contains sertraline, the combination of these two drugs creates what pharmacists describe as a "major drug-dru... Read More

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A 48-year-old male asked:
Dr. Heidi Fowler
Psychiatry 25 years experience
Do this under: medical supervision. You are tapered off the zoloft and simultaneously started on low dose cymbalta (duloxetine). As the zoloft is lowered, the cymba... Read More
A 48-year-old male asked:
Dr. Heidi Fowler
Psychiatry 25 years experience
Don't know why: you would want to do that. Cymbalta (duloxetine) can help with both anxiety & depression. Zoloft can also treat both anxiety & depression. Co... Read More
A 48-year-old male asked:
Dr. Shariq Refai
Psychiatry 13 years experience
Neither: well one is not generally safer then the other, it all depends on which works for you. it also depends on what you are treating and what other medicat... Read More
A 48-year-old male asked:
Dr. Michael Roman
Internal Medicine 26 years experience
Talk to: your doctor about the best treatment for you. You want to maximize treatment. So discuss the best options with your doctor
A 23-year-old female asked:
Dr. Shariq Refai
Psychiatry 13 years experience
Generally: Some medications dont exactly cause weight gain but if you feel depressed sometimes you dont eat so when you take an antidepressant and start feeling ... Read More
A 48-year-old male asked:
Dr. Marsha Davis
Internal Medicine 28 years experience
Not sure: Maybe because you thought the Cymbalta (duloxetine) helped with sleep. It is not a sleeping drug. It is for moods. Maybe it is time to have your traza... Read More
A 21-year-old female asked:
Dr. Pamela Pappas
Psychiatry 42 years experience
Antidepressants: Despite the claims of some drug reps, there's really no one antidepressant that is "better" than all others. It's more a case of selecting the one th... Read More
A 32-year-old male asked:
Dr. Marcie Berman
Clinical Psychology 39 years experience
Newest are cleanest: Each new generation of SSRIs is supposedly cleaner than originals. Lexapro or Celexa may be worth trying. Also, Paxil (paroxetine) is less activati... Read More
A 73-year-old female asked:
Dr. Edward Smith
Neurosurgery 54 years experience
Depends on drug: Certain drugs, which are Dopamine antagonists (typically drugs for psychosis, mood disorders, ocd, and some antihypertensives) can cause parkinson-lik... Read More

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