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Is it good to combine Prozac with wellbutrin for treatment of depression

A 40-year-old member asked:
Dr. Glenn Archibald
Psychiatry 38 years experience
It is good, sort of.: It depends. There is no absolutes in medicine. However, it is not unusual to combine antidepressants if the initial does not work. Prozac and wellbutr... Read More
Dr. Douglas Bey
Psychiatry 58 years experience
May be: Wellbutin blocks the uptake of norepinephrine & Dopamine while Prozac (fluoxetine) is a ssris so they effect different neurotransmitters & may work 4 ... Read More
Dr. Alan Ali
Dr. Alan Alianswered
Psychiatry 33 years experience
Prozac (fluoxetine): Assuming wellbutrin (bupropion) is at maximum dose and still no response, sometimes Prozac can be booster, taking it in morning & wellbutrin (bupropio... Read More

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A 39-year-old female asked:
Dr. John Gaffney
Psychiatry 26 years experience
Use alternative: Unfortunately Prozac (while an awesome drug) can interact with quite a few medications. Usually the SSRI + Wellbutrin (bupropion) combo is a great and... Read More
Dr. Judith Tellerman
Clinical Psychology 43 years experience
MEDICATION: Best to discuss medication with your Psychiatrist. If uncomfortable with your Dr. consult another for a second opinion. Have a physical exam by a Dr. ... Read More
A 56-year-old female asked:
Dr. Donald Gieck
Clinical Psychology 15 years experience
Not effective?: Need more information to understand your primary concern - is your concern the regimen is not effective, or too much? or is your concern with the regi... Read More
A 23-year-old female asked:
Dr. Jeffrey Unger
A Verified Doctoranswered
42 years experience
Dont know: Too many questions which cannot be answered in this format. I'd suggest that you'd be screened for sleep disorders which can impair memory.
A 39-year-old female asked:
Dr. Oleksandr Osipchuk
Specializes in Psychiatry
Sure: Could be very powerful combination because they are from different classes of medications; dose proportion of both med's is very important.
A 33-year-old female asked:
Dr. Kathy Robinson
Family Medicine 33 years experience
For some people: This type of treatment has to be individualized for each person. Wellbutrin is good for depression but could make anxiety worse in some patients. Proz... Read More
A member asked:
Dr. Elizabeth Finley-Belgrad
Child Psychiatry 35 years experience
Talk to prescriber : Wellbutrin 1/2 life -the time it take for 1/2 to be out of the body is 33-37 hrs so really the fastest, the prozac is 2-4 d , but has an active metabo... Read More
A 24-year-old male asked:
Dr. Harold Fields
Family Medicine 62 years experience
Meds : It is a long of medication but if taken as prescribed should not cause you any problem
A 18-year-old female asked:
Dr. Jonathan Stoudmire
Psychiatry 22 years experience
Yes it could be: While Wellbutrin (bupropion) can be an effective antidepressant for some people, a possible side effect is an increase in depression.