Question 1

what causes neuroleptic malignant syndrome?

Accepted Answer

NMS: Is acute reaction to antipsychotic meds. With fever, confusion and other symptoms of increased metabolism, along with inc. Liver enzymes. Is a medical emergency and treated in er.

Question 2

how do you treat neuroleptic malignant syndrome?

Accepted Answer

Supportive: Mainly supportive treatment by controlling blood pressure, oxygenation, cardiac irregularity, electrolyte water balance, seizure treatment. Some drugs are used that seem to be helping.

Question 3

who is at risk of neuroleptic malignant syndrome?

Accepted Answer

NMS: Mms can occur with use of neuroleptics, mostly older ones such as thorazine, much less so with newer ones like abilify (aripiprazole). Also depends on dose.

Question 4

can you please define neuroleptic malignant syndrome?

Accepted Answer

NMS: Is acute reaction to antipsychotic meds. With fever, confusion and other symptoms of increased metabolism, along with inc. Liver enzymes. Is a medical emergency and treated in er.

Question 5

what are the tests for neuroleptic malignant syndrome?

Accepted Answer

Several!: Neuroleptic malignant syndrome is a diagnosis of exclusion, so we have to make sure there isn't another problem like an infection.

Blood count may show high white blood cells, urine test may have myoglobin.  If  tests like blood and urine culture show no signs of infection, ct/mri of the head show no brain problems and the patient is on or has taken an antipsychotic this points us towards nms.

Question 6

what are the symptoms of neuroleptic malignant syndrome?

Accepted Answer

Fever, stiff muscles: Fever, stiff muscles, changes in personality and thinking, and autonomic instability (racing heart, low or high blood pressure, sweating, leaking urine...) are symptoms of neuroleptic malignant syndrome.

This is a very serious and life-threatening reaction to treatment with antipsychotic medications or withdrawal from certain medications.

Question 7

could you explain what is neuroleptic malignant syndrome?

Accepted Answer

Complicated : "life-threatening condition that may develop anytime during therapy with neuroleptics—from a few days to many years (but 2/3 of cases occur within the 1st week).
Muscular rigidity from Dopamine antagonism in the nigrostriatal pathway. 
Hyperthermia due to blockage of hypothalamic thermoregulation (more likely in the setting of benzodiazepine withdrawal)" from lexi drugs.

Question 8

what is the definition or description of: neuroleptic malignant syndrome?

Accepted Answer

Rare &amp; Dangerous: Neuroleptic malignant syndrome is a rare, potentially life-threatening disorder usually caused by an unpredictably bad reaction to an antipsychotic drug. Typically there is muscle rigidity, fever, unstable pulse and blood pressure, mental impairments and characteristic laboratory changes.  Treatment relies on stopping the drug and supportive hospital care.

Question 9

of all the health problems, why would i get neuroleptic malignant syndrome?

Accepted Answer

Medication effect: This is a rare but serious problem which is usually related to taking medications for psychiatric treatment, or sometimes for Parkinson's disease.  It causes fever, muscle rigidity, unstable blood pressure and other problems.  The medication causing nms must be identified and discontinued.  If you ever need anesthesia, be sure to tell the anesthesiologist if you've had this problem.

Question 10

can you tell me how are you supposed to treat neuroleptic malignant syndrome?

Accepted Answer

Complicated: This should be done by medical professionals. Correct diagnoses is also very important. There are no specific medication. Every case is different.

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