A member asked:

What are the symptoms of neuroleptic malignant syndrome?

6 doctors weighed in across 2 answers

Fever, stiff muscles: Fever, stiff muscles, changes in personality and thinking, and autonomic instability (racing heart, low or high blood pressure, sweating, leaking urine...) are symptoms of neuroleptic malignant syndrome. This is a very serious and life-threatening reaction to treatment with antipsychotic medications or withdrawal from certain medications.

Answered 3/11/2015

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Dr. James Schlichting answered

Specializes in Medical Psychotherapy

NMS is a life threatening condition that results from dopamine receptor antagonists (antipsychotics potential offenders) or withdrawal of a dopamine promoting medication. The symptoms include mental status changes, fever, muscle rigidity or autonomic instability. An example of ai is tachycardia where the heart rate is elevated. Remove offending drug, supportive care, consider need for meds

Answered 3/15/2023

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