How do you treat neuroleptic malignant syndrome?

Supportive: Mainly supportive treatment by controlling blood pressure, oxygenation, cardiac irregularity, electrolyte water balance, seizure treatment. Some drugs are used that seem to be helping.

Emergency : The most important thing is to stop any antipsychotic medication. Supportive treatment in a closely monitored setting. Some medications like bromocriptine or amantadine may also be used.

Removal of the offending agent, aggressive supportive care, and certain pharmacological therapy in severe cases. Bromocriptine mesylate, a dopamine agonist (promotes dopamine) and dantrolene sodium for the muscle rigidity (a muscle relaxant) are considerations. In cases secondary to removal of a dopaminergic drug, improvement can happen with re-introducing it