Question 1

hepatocellular carcinoma.all spleen and partial liver resection.later,secondary systemic cancer metastasis.any targeted therapy or immunotherapy?

Accepted Answer

Yes, for both: Hepatocellular Carcinoma is commonly treated with Sorafenib which is a type of targeted therapy. This is a good choice of treatment in case you have not yet received this drug. Immunotherapy using PD-1 inhibitors has also shown some modest evidence of benefit although it is not yet FDA approved for this indication. Ask your oncologist to guide your treatment further.

Question 2

does a new diagnosis of hepatocellular carcinoma add points to the meld score of a cirrhosis patient? patient is going to be evaluate for transplant.  hepatologist has not started testing to see if hcc is primary or a metastasis?  shouldn't they be doing

Accepted Answer

HCC : Hcc is, by definition, primary in the liver.  If the tumor size and quantity fit within very specific criteria, then the patient is given extra points toward transplant.  However, if the tumor burden exceeds those limits or has metastasized outside of the liver, then the patient is not a candidate for transplant regardless of the meld score. If a tumor is smaller than 2 cm, it is not counted towards transplant

the criteria i've mentioned are called the milan criteria.  They specify the following: in order to qualify for transplant, a patient can have one hcc lesion up to 5 cm in size or as many as three hcc lesions as long as none of them is larger than 3 cm.

Question 3

whats treatment for small early hepatocellular carcinoma?

Accepted Answer

LIVER TRANSPLANT: Liver transplant is the best option for cure.  You need referal to a transplant center and be seen by a multispecialty team. Since it may take time to obtain a liver there are certain therapies that are used as a bridge to transplant. Radiofrequency ablation - burning of tumor. Chemoembolization - infusing chemotherapy into tumor and then blocking the artery that feeds it.

Question 4

how is the prognosis and treatment for early hepatocellular carcinoma?

Accepted Answer

Depends on therapy: Its really therapy dependent.  Most hcc are related to cirrhosis, usually extensive and multiple and not amenable to therapy.  Only early hcc can be amenable to resection and or liver transplant.  Transplant is curative, as can be resection in the absence of cirrhosis, especially for early (modified ajcc stage 1 or 2) hcc 
most other therapies are largely palliative and offer dismal long term surv.

Question 5

please tell me is there any cure or treatment for hepatocellular carcinoma and please guide me i  am confused about it?

Accepted Answer

Depends: Depends on how advanced it is, my friend. Early hcc may be treated successfully, maybe even cured, with surgery but therapy for more advanced ones is directed mostly to shrink and control the cancer rather than curing it. It also depends on how healthy the patient is in general. Idealy should be managed in a multidisciplinary setting (surgeons, transplant specialists, gi, and medical oncologist).

Question 6

my wife 42, after total thyroidectomy surgery , a month later she received i-133 therapy 120 units. full body scan shows no metastasis. prognosis of it?

Accepted Answer

Good prognosis: In thyroid cancers over all prognosis is excellent.. It is good she has ' no metastasis '     need more information , histological type , when  surgery was done , is there any any metastasis at that time, her age  etc . Stage of the disease is important to predict prognosis . Most common type is papillary cancer of thyroid , which has very good out come . Good luck.

Question 7

my dad,70yo with polycitemia (therapy= hidroxiurea).found 3 squamous cell carcinomas in face. are 2 carcinomas metastasis/diffusion of the first one?

Accepted Answer

Multiple primaries: Skin cancers often pop up in multiple places around the same time due to longstanding sun exposure. It's important to know this isn't spread.

Question 8

my grandfather (80) has hepatocellular carcinoma (t2n0m0). he then got resection. besides regular check up now, is there any other treatment a patient like him can typically take post operation? what about health supplement? thanks?

Accepted Answer

See below: Health supplements are usually not useful.  He should not take any medication, including over the counter drugs, herbals or so called health supplements without discussing it with his doctor.

Question 9

dad is 68, recently diagnosed with advaced prostate cancer with skeletal bone metastasis. what kind of hormone therapy shall he use?

Accepted Answer

Multiple available: There are multiple hormonal and non-hormonal therapies available. Your dad desperately needs a visit to a urologist and a cancer specialist, and maybe a radiotherapist. Get him in for a visit quickly!

Question 10

my dad is 68 years old. recently, he was dignosed with advanced prostate cancer with skeletal bone metastasis. what kind of hormone therapy shall he use? is orchiectomy ok?

Accepted Answer

Yes: Orchiectomy is nearly instantly effective in reducing testosterone levels and can be done as an outpatient. Alternatives include injections (lhrh agonists) to reduce testosterone levels. These are relatively expensive over the long term, but preserve the testicles which is why many men prefer this option. Surgery is permanent whereas shots can be withheld, but permanent may be best with bone mets.

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Doctor answers about:

Hcc metastasis Targeted therapy

A member asked:

Hepatocellular carcinoma.all spleen and partial liver resection.later,secondary systemic cancer metastasis.any targeted therapy or immunotherapy?

A member asked:

Does a new diagnosis of hepatocellular carcinoma add points to the meld score of a cirrhosis patient? patient is going to be evaluate for transplant. hepatologist has not started testing to see if hcc is primary or a metastasis? shouldn't they be doing

A member asked:

Whats treatment for small early hepatocellular carcinoma?

A member asked:

How is the prognosis and treatment for early hepatocellular carcinoma?

A member asked:

Please tell me is there any cure or treatment for hepatocellular carcinoma and please guide me i am confused about it?

A member asked:

My wife 42, after total thyroidectomy surgery , a month later she received i-133 therapy 120 units. full body scan shows no metastasis. prognosis of it?

A member asked:

My dad,70yo with polycitemia (therapy= hidroxiurea).found 3 squamous cell carcinomas in face. are 2 carcinomas metastasis/diffusion of the first one?

A member asked:

My grandfather (80) has hepatocellular carcinoma (t2n0m0). he then got resection. besides regular check up now, is there any other treatment a patient like him can typically take post operation? what about health supplement? thanks?

A member asked:

Dad is 68, recently diagnosed with advaced prostate cancer with skeletal bone metastasis. what kind of hormone therapy shall he use?

A member asked:

My dad is 68 years old. recently, he was dignosed with advanced prostate cancer with skeletal bone metastasis. what kind of hormone therapy shall he use? is orchiectomy ok?

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