Question 1

what are the symptoms of graft-versus-host disease?

Accepted Answer

There can be many...: Acute GVHD presents as a skin rash, gut symptoms (nausea or diarrhea) or jaundice.  Chronic GVHD commonly causes dry eyes and dry mouth but they can also get quite sore. More serious symptoms of chronic GVHD include sclerosis (scarring or thickening) of the skin, or reduced flexibility due to connective tissue inflammation (fascitis). Pulmonary airflow obstruction may cause shortness of breath.

Question 2

what is the medical definition of graft-versus-host disease?

Accepted Answer

GVHD: occurs when bone marrow stem cells and/or immune cells have been engrafted from one individual into another. Except in identical twins, differences in cellular antigens cause engrafted cells to react against the host tissues and cause an inflammatory injury. Acutely, symptoms may affect the skin, liver, or gut; whereas chronic GVHD may affect the eyes, mouth, fascia, and lungs.

Question 3

can radiology be used to diagnose graft-versus-host disease?

Accepted Answer

Physical examination: ...and biopsies are the mainstay of diagnosis of graft vs. host disease. Radiology is used mostly to exclude other causes of symptoms, such as an ultrasound of the liver to exclude biliary obstruction, or CT of the chest to exclude infection.

Question 4

what is the difference between graft-versus-host disease and rejection?

Accepted Answer

GVHD is a reaction..: of engrafted immune cells against the patients healthy tissues. It leads to inflammation and side effects in a variety of tissues.  Rejection is the opposite. It is a reaction of the patients immune system against the engrafted cells. In the case of a bone marrow transplant, rejection would cause disappearance of the cells in the marrow and a drop in blood cell production.

Question 5

looking for top specialist for overlapping graft vs host disease. husband suffering from steroid refractory skin gvhd.  nothing works. ?

Accepted Answer

GvHD can be: Challenging. Photophoresis can be a nice adjunct if is available at your treatment center.  This is a complex area and details of past therapy needed to give specific thoughts.

Question 6

is it typical to get graft vs. host digestive problems in first 90 days after bone marrow transplant? how does this affect long term prognosis?

Accepted Answer

Yes: It can happen within first 3 months or after. Graft vs host disease that is not too severe can be a sign of the graft vs leukemia effect but severe gvhd can itself cause mortality.

Question 7

is it true that with bone grafting, all-on-four and etc, mostly anyone can get dental implants even if they lost teeth from gum disease?

Accepted Answer

Limitations: There are limitations to all treatments.  For example, you can get periodontal disease around implants.  Please see your Dentist for an evaluation as to whether implants and crowns or implant supported dentures would be applicable for your situation.  Your Dentist may recommend teaming with an Oral Surgeon or Periodontist, or may recommend that you see a Prosthodontist.  Go for exam and advice.

Question 8

is it okay to drink alcohol, specifically wine 1 week after having a gum graft surgery? when is it safe to have a drink? not taking prescription pain medication, only occasional ibuprofen. my graft was 8 days ago, is it safe to drink now?

Accepted Answer

: I do not see a contraindication of drinking wine one week after the grafting.

Question 9

does  a person who had a bone graft have to take anti rejection drugs?

Accepted Answer

No: The bone graft failed due to a particular reason.  Your doctor should have an idea why.  Usually a different type of bone graft will be performed for the second attempt.  Anti rejection drugs are usually not needed bone grafts.

Question 10

can you leave your underwear on while bone grafting?

Accepted Answer

Ususally not: If you are getting a bone graft and that is your concern express that to your surgeon. He should protect your modesty.

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Doctor answers about:

Graft versus host disease medication

A member asked:

What are the symptoms of graft-versus-host disease?

A member asked:

What is the medical definition of graft-versus-host disease?

A member asked:

Can radiology be used to diagnose graft-versus-host disease?

A member asked:

What is the difference between graft-versus-host disease and rejection?

A member asked:

Looking for top specialist for overlapping graft vs host disease. husband suffering from steroid refractory skin gvhd. nothing works. ?

A member asked:

Is it typical to get graft vs. host digestive problems in first 90 days after bone marrow transplant? how does this affect long term prognosis?

A member asked:

Is it true that with bone grafting, all-on-four and etc, mostly anyone can get dental implants even if they lost teeth from gum disease?

A member asked:

Is it okay to drink alcohol, specifically wine 1 week after having a gum graft surgery? when is it safe to have a drink? not taking prescription pain medication, only occasional ibuprofen. my graft was 8 days ago, is it safe to drink now?

A member asked:

Does a person who had a bone graft have to take anti rejection drugs?

A member asked:

Can you leave your underwear on while bone grafting?

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