Question 1

interested to know if people with sickle cell anemia usually get splenectomies?

Accepted Answer

Sometimes: Occasionally patients with sickle cell disease will have a splenectomy.  It usually occurs if the spleen gets to large and it is life-threatening.

Question 2

do people with sickle cell anemia have higher chance of having a cerebrovascular accident (stroke)?

Accepted Answer

Yes.: Sickle cells can clog blood vessels causing small strokes (embolic); they can also damage blood vessel walls making them more susceptible to tearing and bleeding and leading to strokes (hemorrhagic). Keeping blood pressure and diabetes under control and keeping the percentage of sickle cells low can be helpful.

Question 3

can people with sickle cell anemia donate blood?

Accepted Answer

No: A diagnosis of sickle cell disease precludes donation of blood. This is not only because of the presence of the disease itself, but also because patients with sickle cell disease fail to meet the hemoglobin criteria for donors set by the red cross, which is 12.5g/dl.

Question 4

why do people with sickle cell anemia suffer from leg ulcers?

Accepted Answer

Blood flow and oxyge: Sickle cells both slow blood flow and decrease oxygen carrying capacity of blood leading to ulcers.  Try nitro paste near not on ulcer.

Question 5

what to do if i have to do a report on sickle cell anemia and i was wondering do people with sickle cell anemia usually get splenectomies?

Accepted Answer

No: The disease usually results in the self destruction of the spleen as a functional organ by the age 3. At that point it would have no impact on the disorder and cease to be of any importance.

Question 6

could two people with sickle cell trait give their child sickle cell anemia?

Accepted Answer

Yes: Or one with trait and one with ss.

Question 7

is sickle cell anemia a severe condition?

Accepted Answer

Depends: It depends on the type of sickle cell disease a patient has, and how many attacks they get in a year and how severe those attacks are.

Question 8

can sickle-cell anemia be detected from a test?

Accepted Answer

Yes: Certain blood work - i.e. Cbc, and a hemoglobin electrophoresis, - would need to be done to establish a diagnosis of sickle cell anemia.

Question 9

can you explain a punnet square of sickle cell anemia ?

Accepted Answer

In 400 words?: This sounds like homework. 
This is simple mendelian genetics, the old 1:2:1 ratio of outcomes if two carriers mate.  So if two sickle carriers mate, 1/4 offspring will be wild-type, 2/4 will be carriers, and 1/4 will have full-blown sickle cell disease.
http://www.ndsu.edu/pubweb/~mcclean/plsc431/mendel/mendel1.htm.

Question 10

how long does a person with sickle cell anemia usually live?

Accepted Answer

In general: 50% of patients with sickle cell anemia survive beyond the 5th decade. Early mortality is high among patients whose disease is symptomatic. A high level of fetal hemoglobin predicts improved survival.

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A member asked:

Interested to know if people with sickle cell anemia usually get splenectomies?

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Do people with sickle cell anemia have higher chance of having a cerebrovascular accident (stroke)?

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Can people with sickle cell anemia donate blood?

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Why do people with sickle cell anemia suffer from leg ulcers?

A member asked:

What to do if i have to do a report on sickle cell anemia and i was wondering do people with sickle cell anemia usually get splenectomies?

A member asked:

Could two people with sickle cell trait give their child sickle cell anemia?

A member asked:

Is sickle cell anemia a severe condition?

A member asked:

Can sickle-cell anemia be detected from a test?

A member asked:

Can you explain a punnet square of sickle cell anemia ?

A member asked:

How long does a person with sickle cell anemia usually live?

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