Question 1

does inbreeding in families cause hemophilia to develop?

Accepted Answer

Not usually: Despite emphasis on hemophilia and royal families, rasputin's influence depended on common  relatives among english/russian royalty. The well-known hemophilias are x-linked, passed through normal women with 2 xs to men with one. Inbreeding increases chances for matching up of rare, autosomal recessive mutations in spouses (e.g., cystic fibrosis, tay-sach's diseases).

Question 2

what are some organizations that can help a family cope with a child's hemophilia?

Accepted Answer

Hemophilia groups: The hemophilia websites i find most valuable (and accurate) belong to the national hemophilia foundation and world federation of hemophilia.

Question 3

my sister has a son with hemophilia, but there is no family history other than that, is this just bad luck?

Accepted Answer

Perhaps: Hemophilia a & b are x-linked recessive while c is usually autosomal recessive.  So, it's possible that the mother was a carrier.  However, about 1/3 of a & b cases are due to spontaneous mutation.

Question 4

what type of mutation causes hemophilia?

Accepted Answer

Hemophilia: A mutation on the x chromosome that affects the blood clotting factors viii or ix.

Question 5

can you tell me how bleeding cause hemophilia?

Accepted Answer

It dosent: The bleeding is not the cause of this condition but the sign of the disorder. The person with hemophilia lacks some of the factors responsible         for clotting. Thus any bleeding lasts for a longer time and is more profound as compared to a person with normal clotting mechanisms.

Question 6

what type of mutations that cause hemophilia a?

Accepted Answer

Gene on X-chromosome: Hemophilia a is a hereditary bleeding disorder where there is a deficiency in clotting factor viii (factor viii is needed for blood clotting). It is inherited on the x-chromosome (sex-linked). Men only have 1 "x", so if their "x" is mutated, they will have the disease. Women have 2 "x's", so they can have 1 mutated "x" and 1 normal "x", and be a carrier of the disease, with mild or no symptoms.

Question 7

can excessive use of antibiotics cause prolonged pt in patients with hemophilia?

Accepted Answer

Yes: Some classes of antibiotics can prolong the prothrombin time, especially when taken with other medications.  Your doctor should be aware of all of your medical conditions, all medications (including herbs and vitamins), and any subsequent symptoms.  This can be dangerous and needs close monitoring and frequent lab work.

Question 8

does hemophilia only affect men?

Accepted Answer

It is more likely: Hemophilia mostly affects men. It is rare but not impossible for a female to have hemophilia. Hemophilia is a sex-linked recessive disorder: the trait is carried on the x chromosome which a female has two of and a male only has one. This means a female would have to inherit two copies of the hemophilia gene to have the disorder. A male only has to inherit one copy.

Question 9

who is at risk of having hemophilia?

Accepted Answer

It's genetic: True hemophilis is a genetic disease, and you either have it or you do not. The severity is widely variable -- there's even a professional prizefighter who discovered he had it. If you bruise easily or are a child with an affected relative, lab testing is easy.

Question 10

how do you get tests for hemophilia?

Accepted Answer

Blood test: If suspected any doctor can order a blood test for hemophilia.  There are two major types with deficiceny of different clotting factors, hemophilia a has deficincy of factor viii and hemophilia b of factor ix.  Most hospital labs can do the testing on blood sample to make the diagnosis.

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Does inbreeding in families cause hemophilia to develop

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Does inbreeding in families cause hemophilia to develop?

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What are some organizations that can help a family cope with a child's hemophilia?

A member asked:

My sister has a son with hemophilia, but there is no family history other than that, is this just bad luck?

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What type of mutation causes hemophilia?

A member asked:

Can you tell me how bleeding cause hemophilia?

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What type of mutations that cause hemophilia a?

A member asked:

Can excessive use of antibiotics cause prolonged pt in patients with hemophilia?

A member asked:

Does hemophilia only affect men?

A member asked:

Who is at risk of having hemophilia?

A member asked:

How do you get tests for hemophilia?

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