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A member asked:
My sister has a son with hemophilia, but there is no family history other than that, is this just bad luck?
8 doctors weighed in across 2 answers
Perhaps: Hemophilia a & b are x-linked recessive while c is usually autosomal recessive. So, it's possible that the mother was a carrier. However, about 1/3 of a & b cases are due to spontaneous mutation.
Answered 1/31/2012
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Spontaneous mutation: About a third of the cases of the two most common causes of hemophilia are due to spontaneous mutations.
Answered 12/22/2013
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