Question 1

are there other alternatives to enbrel (etanercept) and humira?

Accepted Answer

Yes: It depends on the disease being treated. For
psoriasis (my field is dermatology), there is
infliximab (remicade), ustekinemab (stelara), 
alefacept (amevive) - not used much now and golimumab (simponi) - not used much either.

Question 2

i was on humira and felt terrible, is enbrel (etanercept) any better?

Accepted Answer

It's different: Different people react differently to different medications. It is possible that you will have the same trouble with Enbrel (etanercept) but it's also possible that you will have no trouble with enbrel (etanercept). The only way to know for certain is to try it.

Question 3

what is the difference in mechanism or humira and enbrel (etanercept)?

Accepted Answer

None: There both basically work by the same mechanism which is inhibition of tnp.

Question 4

what's average amount of time people can take biologics (ex: humira (adalimumab) or enbrel) before developing an immunity to it? do all patients develop immunity?

Accepted Answer

See below: Patients are more apt to develop resistance to biologic if they are not on methotrexate.  However; not all patients are candidate to be on methotrexate.   Some patients never have a problem and some do.  It is hard to comment on the average amount of time because it is an individual phenomena.

Question 5

is there a waiting period between changing from enbrel (etanercept) to humira? if so, how long? then how long before humira begins to work?

Accepted Answer

No: No waiting period needed   humors should yield reasonable benefit within 4-6 weeks.  I personally have not seen that going with one tnf agent to another produces better results.

Question 6

is there a difference in humira and enbrel (etanercept) treatment of psoriasis?

Accepted Answer

No great...: No great differences. Enbrel (etanercept) is once weekly and Humira is once every two weeks. They have similar efficacy in large trials, but differences exist between individuals! both should be tried only after Methotrexate therapy has failed!

Question 7

with other tnf inhibitors such as humira and enbrel (etanercept) are there?

Accepted Answer

See below: Cimzia (certolizumab pegol), simponi (golimumab), and Remicade (infliximab) are the other tnf Alpha inhibitors available in the United States.

Question 8

what are the side effects of tnf inhibitors such as humira and enbrel (etanercept)?

Accepted Answer

See below: The important side effects that have been most extensively related to tnf blockers include: lymphoma, infections including tuberculosis, congestive heart failure, demyelinating disease, a lupus-like syndrome, induction of auto-antibodies, injection site reactions, and systemic side effects.

Question 9

was on humira (adalimumab) weekly&psoriasis came back. now on enbrel&25mg methotraxte.do u think psorias will clear?y did humira (adalimumab) stop working?stress overpower it?

Accepted Answer

Both work: It's your these medicines are effective. The reason medication stop working may depend on many factors. Sometimes the body develops resistance to a medication that is working fine. The resistance can occur  because of antibodies against the drug. It can also occur because the mechanism of the disease of the illness can change differently at the molecular level. You doctor can better answer this.

Question 10

dx:ra. enbrel (etanercept) not effective after 6 mo. humira 2x mo prescribed. liver can not tolerate mtx. what medication can replace mtx to make humira work best?

Accepted Answer

See a rheumatologist: The only person who should be advising you on this is a doctor who is seeing you and examining you and has your entire medical history available. There  are several ways to approach this and decisions must be made only after a face to face encounter.  Hope you get this worked out soon.  Best.

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Doctor answers about:

Alternatives to humira enbrel

A member asked:

Are there other alternatives to enbrel (etanercept) and humira?

A member asked:

I was on humira and felt terrible, is enbrel (etanercept) any better?

A member asked:

What is the difference in mechanism or humira and enbrel (etanercept)?

A member asked:

What's average amount of time people can take biologics (ex: humira (adalimumab) or enbrel) before developing an immunity to it? do all patients develop immunity?

A member asked:

Is there a waiting period between changing from enbrel (etanercept) to humira? if so, how long? then how long before humira begins to work?

A member asked:

Is there a difference in humira and enbrel (etanercept) treatment of psoriasis?

A member asked:

With other tnf inhibitors such as humira and enbrel (etanercept) are there?

A member asked:

What are the side effects of tnf inhibitors such as humira and enbrel (etanercept)?

A member asked:

Was on humira (adalimumab) weekly&psoriasis came back. now on enbrel&25mg methotraxte.do u think psorias will clear?y did humira (adalimumab) stop working?stress overpower it?

A member asked:

Dx:ra. enbrel (etanercept) not effective after 6 mo. humira 2x mo prescribed. liver can not tolerate mtx. what medication can replace mtx to make humira work best?

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