Are there other alternatives to enbrel (etanercept) and humira?

Yes: It depends on the disease being treated. For psoriasis (my field is dermatology), there is infliximab (remicade), ustekinemab (stelara), alefacept (amevive) - not used much now and golimumab (simponi) - not used much either.

Yes: There are alternatives that don't require you to inject yourself, alternatives that are given by intravenous, and alternatives that work in an entirely different way on a different part of your immune system, for rheumatoid arthritis, psoriatic arthritis, Crohn's disease.

Many!: Methotrexate, sulfasalazine, Imuran, and other non-biologics. Other TNF-alpha inhibitors exist, such as Simponi and Remicade!