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A member asked:
Buspar (buspirone) and zoloft do they interact?
7 doctors weighed in across 3 answers
Yes: Both drugs effect serotonin. Combined at high doses there is a risk of a toxic effect. On the other hand, Buspar (buspirone) can enhance the effect of antidepressants like zoloft when depression has been refractory to treatment.
Answered 5/18/2015
5.2k views
Good mix often: Yes- usually very nicely. Buspar (buspirone) is a great adjunct for a patient with an anxious depression or with an anxiety disorder. The ssri dose would have to be quite high for Buspar (buspirone) to push over the edge into a serotonin syndrome.
Answered 5/23/2018
5.2k views
Zoloft/Buspar: Some nausea or headaches, otherwise ok. Recommend on full stomach.
Answered 4/3/2015
3k views
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Can Buspar (buspirone) bi stop without tapering wille augmenting Zoloft and there any defecolt withdraw from buspar (buspirone)?
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Hi everybody. I have been put on Buspar (buspirone) 5 mg a day, add-on to my 200mg zoloft. It's been 9 weeks and no change. What can be done.
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