Can you take perscriptions zoloft, buspar (buspirone) and valium together?

Yes: Combination therapy is very common in medicine. If each medication was carefully chosen for certain symptoms or condition, it can be very beneficial. Keep in mind, each medication has to be taken as prescribed to you only. Unless it was prescribed by your doctor, the above medications, should not be mixed just to see what the effect would be. Eat well, sleep well and live well.

Usually: Usually there is not a problem. However, there is a potential for Serotonergic Syndrome when Zoloft & Busparare combined. Although Serotonin Syndrome could theoretically occur at even a small dose of medications - I have only seen it with high doses of combined serotonergic meds. Any interactions with Valium would likely be mild at most.