What can i do about hypermobility syndrome in my knees?

Strengthen Your Knee: There is no surgery, medication, brace, injection, etc for "hypermobility" of the knees at this point in time. Some individuals collagen simply has more elasticity (stretchiness) to it. The best strategy would be to do strengthening exercises and physical therapy to optimize the quads, hamstrings, hip muscles, and calf muscles which work as secondary stabilizers of the knee.