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A 23-year-old male asked:

When the spermatogonial stem cell get mutated by chemicals, if the mutated sperm fertilize the egg, will the child have de novo genetic defect?

1 doctor answer1 doctor weighed in
Dr. Michael Traub
Fertility Medicine 19 years experience
No: So lots of things cause mutations in sperm and most sperm are not good. That is why it takes millions to get one good sperm. When mutations occur they usually render the sperm less useful and normally that sperm is not going to fertilize and egg

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Last updated Mar 6, 2017

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