Is it safe to drink alcohol while taking lexapro (escitalopram)?

Yes, but...: You may feel like you have had more to drink than you have really had. Use caution, drink slowly, and monitor how you feel before taking your next sip. Assume you can only drink about half as much as you could before being on any psychiatric medication. And if you are just starting the medication and your body is just getting used to it, it may be better not to drink at all.

Not advised: Drinking on an ssri antidepressant can make depression or anxiety persist ("fighting" the treatment). It increases seizure risk. Can make alcohol feel stronger, impairing driving and similar activities more than expected. The standard rule: avoid all alcohol. That said, people use ssris for months or years; some use alcohol occasionally in small amts and are ok. Weigh the risks.