A member asked:

Ana1:640terrible flares >4yrs of fatigue, arthr/myalgia, pleuritic pain, photosen rashes, sicca.exten rheum work up all neg even during flares.rheum tried methotrexate which stoped sx! diagnosis w/neg work up?

A doctor has provided 1 answer
Dr. Arthur Heller answered

Specializes in Gastroenterology

How is it neg?: ANA strongly positive, with multiple symptoms that are consistent with autoimmune disease (likely lupus based on info provided); response to meds used to rx autoimmune disease. Sounds like autoimmune disease.

Answered 8/24/2014

4.9k views

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