A member asked:

Which antidepressant causes weight loss? i've been on many and last one was effexor (venlafaxine) xr as others make me tired. i put on weight. am depressed grieving

12 doctors weighed in across 2 answers
Dr. Pamela Pappas answered

Specializes in Psychiatry

Depressed & grieving: Active grieving of a loss needs support more than medication. If the grief has become depression with poor self esteem, ongoing vegetative signs (changes in sleep, energy, appetite etc), & worthlessness etc antidepressants may help. Wellbutrin (bupropion) does not reliably cause weight loss, but it's less likely to cause weight gain than some others. Lexapro may be relatively weight neutral also.

Answered 12/19/2019

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Dr. Krishna Kumar answered

Specializes in Psychiatry

Weight Loss: Usually, ssri medications like prozac, zoloft, paxil, (paroxetine) Lexapro decrease appetite, thus indirectly may lead to weight loss. Antidepressants should not be used for weight loss, due to various side effects.

Answered 5/16/2016

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