See below: To be overly simplistic, osteoarthritis is considered to be due to wear and tear damage on joints from mechanical forces and is treated primarily with pain medications, weight loss and exercise, while rheumatoid arthritis is cause by the immune (infection fighting) system becoming confused and attacking the joints instead of infectious agents and is treated by drugs that alter the immune system.
Answered 9/15/2012
6.2k views
Very different.: Ra is a destructive, inflammatory, immunological process affecting joints and other body organs. Oa is an insidious, degenerative joint process with less inflammation.
Answered 3/22/2015
5.6k views
Mechanism: RA is an inflammatory arthritis wherein your immune system attacks the cushioning within your joints. OA is destructive from use.
Answered 10/25/2014
3.6k views
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